Title |
Muscle transcriptomic investigation of late fetal development identifies candidate genes for piglet maturity
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Published in |
BMC Genomics, September 2014
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DOI | 10.1186/1471-2164-15-797 |
Pubmed ID | |
Authors |
Valentin Voillet, Magali SanCristobal, Yannick Lippi, Pascal GP Martin, Nathalie Iannuccelli, Christine Lascor, Florence Vignoles, Yvon Billon, Laurianne Canario, Laurence Liaubet |
Abstract |
In pigs, the perinatal period is the most critical time for survival. Piglet maturation, which occurs atthe end of gestation, leads to a state of full development after birth. Therefore, maturity is an importantdeterminant of early survival. Skeletal muscle plays a key role in adaptation to extra-uterine life, e.g.glycogen storage and thermoregulation. In this study, we performed microarray analysis to identifythe genes and biological processes involved in piglet muscle maturity. Progeny from two breeds withextreme muscle maturity phenotypes were analyzed at two time points during gestation (gestationaldays 90 and 110). The Large White (LW) breed is a selected breed with an increased rate of mortalityat birth, whereas the Meishan (MS) breed produces piglets with extremely low mortality at birth. Theimpact of the parental genome was analyzed with reciprocal crossed fetuses. |
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Student > Postgraduate | 2 | 10% |
Student > Ph. D. Student | 1 | 5% |
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Student > Master | 1 | 5% |
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