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Intra-articular hyaluronic acid injection versus oral non-steroidal anti-inflammatory drug for the treatment of knee osteoarthritis: a multi-center, randomized, open-label, non-inferiority trial

Overview of attention for article published in Arthritis Research & Therapy, January 2014
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Title
Intra-articular hyaluronic acid injection versus oral non-steroidal anti-inflammatory drug for the treatment of knee osteoarthritis: a multi-center, randomized, open-label, non-inferiority trial
Published in
Arthritis Research & Therapy, January 2014
DOI 10.1186/ar4446
Pubmed ID
Authors

Muneaki Ishijima, Toshitaka Nakamura, Katsuji Shimizu, Kunihiko Hayashi, Hiraku Kikuchi, Satoshi Soen, Go Omori, Toshihiko Yamashita, Yuji Uchio, Junji Chiba, Yuki Ideno, Mitsuaki Kubota, Hisashi Kurosawa, Kazuo Kaneko, for the Research Group of Cartilage Metabolism

Abstract

While many of the commonly used conservative treatments for knee osteoarthritis (OA) have been recognized to be effective, there is still insufficient evidence available. Among the pharmacological treatments for knee OA, oral non-steroidal anti-inflammatory drugs (NSAIDs) act rapidly and are recommended for the management of OA. However, frequent and serious adverse effects of NSAIDs have been recognized. Intra-articular injections of hyaluronic acid (IA-HA) for the treatment of knee OA have been shown to reduce pain and improve joint function. However, there has been no qualified direct comparison study of the efficacy and safety between IA-HA and NSAIDs for patients with knee OA. The aim of this study was to clarify the efficacy and safety of early-phase IA-HA in comparison to those of NSAIDs for patients with knee OA.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Ireland 1 <1%
Unknown 165 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 29 17%
Other 19 11%
Student > Bachelor 19 11%
Researcher 14 8%
Student > Doctoral Student 11 7%
Other 32 19%
Unknown 43 26%
Readers by discipline Count As %
Medicine and Dentistry 76 46%
Nursing and Health Professions 11 7%
Agricultural and Biological Sciences 7 4%
Neuroscience 5 3%
Pharmacology, Toxicology and Pharmaceutical Science 4 2%
Other 14 8%
Unknown 50 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2015.
All research outputs
#16,048,318
of 25,374,917 outputs
Outputs from Arthritis Research & Therapy
#2,337
of 3,380 outputs
Outputs of similar age
#186,303
of 321,172 outputs
Outputs of similar age from Arthritis Research & Therapy
#32
of 60 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,172 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.