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Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo

Overview of attention for article published in Fibrogenesis & Tissue Repair, October 2014
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Title
Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo
Published in
Fibrogenesis & Tissue Repair, October 2014
DOI 10.1186/1755-1536-7-14
Pubmed ID
Authors

Ellen De Langhe, Carolina Aznar-Lopez, Vanessa De Vooght, Jeroen A Vanoirbeek, Frank P Luyten, Rik JU Lories

Abstract

The pathogenesis of pulmonary fibrosis remains poorly understood. The Wnt signaling pathway regulates fibrogenesis in different organs. Here, we studied the role of two extracellular Wnt antagonists, secreted frizzled-related protein-1 (SFRP1) and frizzled-related protein (FRZB) on lung fibrosis in vitro and in vivo. For this purpose, we used an alveolar epithelial cell line and a lung fibroblast cell line, and the bleomycin-induced lung fibrosis model, respectively.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 8%
Unknown 23 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 24%
Student > Doctoral Student 4 16%
Student > Ph. D. Student 4 16%
Student > Bachelor 3 12%
Other 1 4%
Other 3 12%
Unknown 4 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 24%
Biochemistry, Genetics and Molecular Biology 5 20%
Medicine and Dentistry 5 20%
Pharmacology, Toxicology and Pharmaceutical Science 3 12%
Immunology and Microbiology 1 4%
Other 0 0%
Unknown 5 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2014.
All research outputs
#14,786,597
of 22,765,347 outputs
Outputs from Fibrogenesis & Tissue Repair
#57
of 83 outputs
Outputs of similar age
#139,775
of 253,586 outputs
Outputs of similar age from Fibrogenesis & Tissue Repair
#2
of 2 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 83 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,586 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.