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Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects

Overview of attention for article published in Molecular Autism, October 2014
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  • Good Attention Score compared to outputs of the same age (74th percentile)

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11 X users
1 Facebook page


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Exon resequencing of H3K9 methyltransferase complex genes, EHMT1, EHTM2 and WIZ, in Japanese autism subjects
Published in
Molecular Autism, October 2014
DOI 10.1186/2040-2392-5-49
Pubmed ID

Shabeesh Balan, Yoshimi Iwayama, Motoko Maekawa, Tomoko Toyota, Tetsuo Ohnishi, Manabu Toyoshima, Chie Shimamoto, Kayoko Esaki, Kazuo Yamada, Yasuhide Iwata, Katsuaki Suzuki, Masayuki Ide, Motonori Ota, Satoshi Fukuchi, Masatsugu Tsujii, Norio Mori, Yoichi Shinkai, Takeo Yoshikawa


Histone H3 methylation at lysine 9 (H3K9) is a conserved epigenetic signal, mediating heterochromatin formation by trimethylation, and transcriptional silencing by dimethylation. Defective GLP (Ehmt1) and G9a (Ehmt2) histone lysine methyltransferases, involved in mono and dimethylation of H3K9, confer autistic phenotypes and behavioral abnormalities in animal models. Moreover, EHMT1 loss of function results in Kleefstra syndrome, characterized by severe intellectual disability, developmental delays and psychiatric disorders. We examined the possible role of histone methyltransferases in the etiology of autism spectrum disorders (ASD) and suggest that rare functional variants in these genes that regulate H3K9 methylation may be associated with ASD.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Hong Kong 1 2%
United Kingdom 1 2%
Unknown 61 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 26%
Student > Ph. D. Student 14 22%
Student > Master 7 11%
Student > Bachelor 5 8%
Student > Postgraduate 5 8%
Other 11 17%
Unknown 6 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 20%
Medicine and Dentistry 10 15%
Agricultural and Biological Sciences 9 14%
Neuroscience 8 12%
Psychology 5 8%
Other 10 15%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2015.
All research outputs
of 22,765,347 outputs
Outputs from Molecular Autism
of 666 outputs
Outputs of similar age
of 254,545 outputs
Outputs of similar age from Molecular Autism
of 7 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 666 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.4. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,545 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.