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Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing

Overview of attention for article published in Nature Communications, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
129 X users
facebook
3 Facebook pages
wikipedia
1 Wikipedia page

Citations

dimensions_citation
40 Dimensions

Readers on

mendeley
146 Mendeley
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Title
Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing
Published in
Nature Communications, October 2017
DOI 10.1038/s41467-017-01194-z
Pubmed ID
Authors

Sandra Romero-Hidalgo, Adrián Ochoa-Leyva, Alejandro Garcíarrubio, Victor Acuña-Alonzo, Erika Antúnez-Argüelles, Martha Balcazar-Quintero, Rodrigo Barquera-Lozano, Alessandra Carnevale, Fernanda Cornejo-Granados, Juan Carlos Fernández-López, Rodrigo García-Herrera, Humberto García-Ortíz, Ángeles Granados-Silvestre, Julio Granados, Fernando Guerrero-Romero, Enrique Hernández-Lemus, Paola León-Mimila, Gastón Macín-Pérez, Angélica Martínez-Hernández, Marta Menjivar, Enrique Morett, Lorena Orozco, Guadalupe Ortíz-López, Fernando Pérez-Villatoro, Javier Rivera-Morales, Fernando Riveros-McKay, Marisela Villalobos-Comparán, Hugo Villamil-Ramírez, Teresa Villarreal-Molina, Samuel Canizales-Quinteros, Xavier Soberón

Abstract

Understanding the genetic structure of Native American populations is important to clarify their diversity, demographic history, and to identify genetic factors relevant for biomedical traits. Here, we show a demographic history reconstruction from 12 Native American whole genomes belonging to six distinct ethnic groups representing the three main described genetic clusters of Mexico (Northern, Southern, and Maya). Effective population size estimates of all Native American groups remained below 2,000 individuals for up to 10,000 years ago. The proportion of missense variants predicted as damaging is higher for undescribed (~ 30%) than for previously reported variants (~ 15%). Several variants previously associated with biological traits are highly frequent in the Native American genomes. These findings suggest that the demographic and adaptive processes that occurred in these groups shaped their genetic architecture and could have implications in biological processes of the Native Americans and Mestizos of today.

X Demographics

X Demographics

The data shown below were collected from the profiles of 129 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 146 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 146 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 18%
Researcher 22 15%
Student > Master 22 15%
Student > Ph. D. Student 20 14%
Professor 11 8%
Other 21 14%
Unknown 24 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 46 32%
Agricultural and Biological Sciences 23 16%
Medicine and Dentistry 10 7%
Chemistry 6 4%
Immunology and Microbiology 6 4%
Other 20 14%
Unknown 35 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 114. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2024.
All research outputs
#377,735
of 25,885,956 outputs
Outputs from Nature Communications
#5,945
of 58,891 outputs
Outputs of similar age
#7,793
of 339,818 outputs
Outputs of similar age from Nature Communications
#161
of 1,432 outputs
Altmetric has tracked 25,885,956 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 58,891 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 55.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,818 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 1,432 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.