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Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma

Overview of attention for article published in BMC Cancer, October 2014
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Mentioned by

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3 X users

Citations

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23 Dimensions

Readers on

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41 Mendeley
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Title
Anti-proliferative but not anti-angiogenic tyrosine kinase inhibitors enrich for cancer stem cells in soft tissue sarcoma
Published in
BMC Cancer, October 2014
DOI 10.1186/1471-2407-14-756
Pubmed ID
Authors

Robert J Canter, Erik Ames, Stephanie Mac, Steven K Grossenbacher, Mingyi Chen, Chin-Shang Li, Dariusz Borys, Rachel C Smith, Joe Tellez, Thomas J Sayers, Arta M Monjazeb, William J Murphy

Abstract

Increasing studies implicate cancer stem cells (CSCs) as the source of resistance and relapse following conventional cytotoxic therapies. Few studies have examined the response of CSCs to targeted therapies, such as tyrosine kinase inhibitors (TKIs). We hypothesized that TKIs would have differential effects on CSC populations depending on their mechanism of action (anti-proliferative vs. anti-angiogenic).

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 20%
Student > Bachelor 5 12%
Student > Postgraduate 5 12%
Student > Master 5 12%
Other 4 10%
Other 9 22%
Unknown 5 12%
Readers by discipline Count As %
Medicine and Dentistry 18 44%
Agricultural and Biological Sciences 8 20%
Biochemistry, Genetics and Molecular Biology 4 10%
Nursing and Health Professions 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 1 2%
Unknown 8 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2015.
All research outputs
#14,786,597
of 22,765,347 outputs
Outputs from BMC Cancer
#3,661
of 8,278 outputs
Outputs of similar age
#141,151
of 255,616 outputs
Outputs of similar age from BMC Cancer
#83
of 171 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,278 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 255,616 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.