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Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study

Overview of attention for article published in Journals of Gerontology Series A: Biological Sciences & Medical Sciences, October 2017
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Title
Physical Function Following a Long-Term Lifestyle Intervention Among Middle Aged and Older Adults With Type 2 Diabetes: The Look AHEAD Study
Published in
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, October 2017
DOI 10.1093/gerona/glx204
Pubmed ID
Authors

Denise K Houston, Rebecca H Neiberg, Michael E Miller, James O Hill, John M Jakicic, Karen C Johnson, Edward W Gregg, Van S Hubbard, Xavier Pi-Sunyer, W Jack Rejeski, Rena R Wing, John P Bantle, Elizabeth Beale, Robert I Berkowitz, Maria Cassidy-Begay, Jeanne M Clark, Mace Coday, Linda M Delahanty, Gareth Dutton, Caitlin Egan, John P Foreyt, Frank L Greenway, Helen P Hazuda, Andrea Hergenroeder, Edward S Horton, Robert W Jeffery, Steven E Kahn, Anne Kure, William C Knowler, Cora E Lewis, Corby K Martin, Sara Michaels, Maria G Montez, David M Nathan, Jennifer Patricio, Anne Peters, Henry Pownall, Judith Regensteiner, Helmut Steinburg, Thomas A Wadden, Karen White, Susan Z Yanovski, Ping Zhang, Stephen B Kritchevsky

Abstract

Lifestyle interventions have been shown to improve physical function over the short term; however, whether these benefits are sustainable is unknown. The long-term effects of an intensive lifestyle intervention on physical function were assessed using a randomized post-test design in the Look AHEAD trial. Overweight and obese (BMI ≥25 kg/m 2) middle-aged and older adults (aged 45-76 years at enrollment) with type 2 diabetes enrolled in Look AHEAD, a trial evaluating an intensive lifestyle intervention (ILI) designed to achieve weight loss through caloric restriction and increased physical activity compared to diabetes support and education (DSE), underwent standardized assessments of performance-based physical function including a 4- and 400-m walk, lower extremity physical performance (expanded Short Physical Performance Battery, SPPBexp), and grip strength approximately 11 years post-randomization and 1.5 years after the intervention was stopped (n=3,783). Individuals randomized to ILI had lower odds of slow gait speed (<0.8 m/sec) compared to those randomized to DSE (adjusted OR [95% CI]: 0.84 [0.71-0.99]). Individuals randomized to ILI also had faster gait speed over 4-m and 400-m (adjusted mean difference [95% CI]: 0.019 [0.007-0.031] m/sec, p=0.002, and 0.023 [0.012-0.034] m/sec, p<0.0001, respectively) and higher SPPBexp scores (0.037 [0.011-0.063], p=0.005) compared to those randomized to DSE. The intervention effect was slightly larger for SPPBexp scores among older vs. younger participants (0.081 [0.038-0.124] vs. 0.013 [-0.021-0.047], p=0.01). An intensive lifestyle intervention has modest but significant long-term benefits on physical function in overweight and obese middle-aged and older adults with type 2 diabetes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 191 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 191 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 22 12%
Student > Master 21 11%
Researcher 13 7%
Student > Ph. D. Student 10 5%
Student > Postgraduate 8 4%
Other 29 15%
Unknown 88 46%
Readers by discipline Count As %
Medicine and Dentistry 30 16%
Nursing and Health Professions 26 14%
Sports and Recreations 15 8%
Social Sciences 4 2%
Unspecified 4 2%
Other 17 9%
Unknown 95 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2019.
All research outputs
#15,173,117
of 25,382,440 outputs
Outputs from Journals of Gerontology Series A: Biological Sciences & Medical Sciences
#2,760
of 3,967 outputs
Outputs of similar age
#175,516
of 336,759 outputs
Outputs of similar age from Journals of Gerontology Series A: Biological Sciences & Medical Sciences
#41
of 52 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,967 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.2. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 336,759 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.