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Mendeley readers
Attention Score in Context
| Title |
3D-FISH analysis reveals chromatid cohesion defect during interphase in Roberts syndrome
|
|---|---|
| Published in |
Molecular Cytogenetics, September 2014
|
| DOI | 10.1186/s13039-014-0059-6 |
| Pubmed ID | |
| Authors |
Celine Dupont, Martine Bucourt, Fabien Guimiot, Lilia Kraoua, Daniel Smiljkovski, Dominique Le Tessier, Camille Lebugle, Benedicte Gerard, Emmanuel Spaggiari, Pierre Bourdoncle, Anne-Claude Tabet, Brigitte Benzacken, Jean-Michel Dupont |
| Abstract |
Roberts syndrome (RBS) is a rare autosomal recessive disorder mainly characterized by growth retardation, limb defects and craniofacial anomalies. Characteristic cytogenetic findings are "railroad track" appearance of chromatids and premature centromere separation in metaphase spreads. Mutations in the ESCO2 (establishment of cohesion 1 homolog 2) gene located in 8p21.1 have been found in several families. ESCO2, a member of the cohesion establishing complex, has a role in the effective cohesion between sister chromatids. In order to analyze sister chromatids topography during interphase, we performed 3D-FISH using pericentromeric heterochromatin probes of chromosomes 1, 4, 9 and 16, on preserved nuclei from a fetus with RBS carrying compound heterozygous null mutations in the ESCO2 gene. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 4% |
| Germany | 1 | 4% |
| Unknown | 25 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 26% |
| Researcher | 4 | 15% |
| Student > Master | 4 | 15% |
| Other | 3 | 11% |
| Student > Bachelor | 2 | 7% |
| Other | 4 | 15% |
| Unknown | 3 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 37% |
| Biochemistry, Genetics and Molecular Biology | 8 | 30% |
| Medicine and Dentistry | 3 | 11% |
| Arts and Humanities | 1 | 4% |
| Neuroscience | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 3 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2014.
All research outputs
#17,728,987
of 22,766,595 outputs
Outputs from Molecular Cytogenetics
#209
of 400 outputs
Outputs of similar age
#170,129
of 252,704 outputs
Outputs of similar age from Molecular Cytogenetics
#7
of 7 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 400 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
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We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.