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Evaluation of a new artificial tear formulation for the management of tear film stability and visual function in patients with dry eye

Overview of attention for article published in Clinical Ophthalmology, October 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

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3 tweeters
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

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14 Dimensions

Readers on

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36 Mendeley
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Title
Evaluation of a new artificial tear formulation for the management of tear film stability and visual function in patients with dry eye
Published in
Clinical Ophthalmology, October 2017
DOI 10.2147/opth.s144369
Pubmed ID
Authors

Gail Torkildsen, Mile Brujic, Michael Cooper, Paul Karpecki, Parag Majmudar, William Trattler, Meryl Reis, Joseph Ciolino

Abstract

Artificial tears are the first line of therapy for dry eye disease (DED) and are also the most frequently used treatment approach for this common condition. Despite this, there are few published studies that directly compare the effectiveness of different drop preparations, especially those formulated specifically for dry eye. In this study, we tested a new artificial tear product, Rohto(®) Dry-Aid™, for its ability to relieve the signs and symptoms of DED. The study used a second drop, Systane(®) Ultra, as a positive comparator. This was a prospective, single-center, open-label, parallel-group study comparing the effects of the two products when used continuously over ~30 days (Clinical Trials registration number NCT03183089). Subjects were randomly assigned to one of the two test groups and were monitored 2 and 4 weeks after enrollment. Efficacy endpoints included ocular staining, visual function, and ocular discomfort. Treatment groups had similar ocular staining and ocular comfort scores, and both showed statistically significant ocular discomfort score improvement. Subjects in the Rohto group reported significant improvements in visual tasking activities such as watching television and driving at night. There was also a tendency for diary symptom scores to worsen from morning to evening in the Systane group, but not in the Rohto group; this trend was not significant, but warrants further study. The two products, Rohto Dry-Aid and Systane Ultra, elicited comparable effects on the signs and symptoms of DED. While both products are designed to provide long-lasting relief, subjects in the Rohto group experienced a superior relief from discomfort associated with visual tasking activities and daily diaries, indicating that the Rohto drops may provide a longer duration of symptomatic relief over the course of the day.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 14%
Researcher 5 14%
Student > Master 4 11%
Other 3 8%
Lecturer 3 8%
Other 6 17%
Unknown 10 28%
Readers by discipline Count As %
Nursing and Health Professions 8 22%
Medicine and Dentistry 6 17%
Biochemistry, Genetics and Molecular Biology 3 8%
Psychology 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 4 11%
Unknown 12 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2017.
All research outputs
#7,226,589
of 23,006,268 outputs
Outputs from Clinical Ophthalmology
#662
of 3,234 outputs
Outputs of similar age
#116,682
of 322,471 outputs
Outputs of similar age from Clinical Ophthalmology
#11
of 29 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 3,234 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,471 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.