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Mediterranean Diet and Low-grade Subclinical Inflammation: The Moli-sani Study

Overview of attention for article published in Endocrine, Metabolic & Immune Disorders - Drug Targets, March 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#1 of 216)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
26 news outlets
facebook
1 Facebook page

Citations

dimensions_citation
38 Dimensions

Readers on

mendeley
64 Mendeley
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Title
Mediterranean Diet and Low-grade Subclinical Inflammation: The Moli-sani Study
Published in
Endocrine, Metabolic & Immune Disorders - Drug Targets, March 2015
DOI 10.2174/1871530314666141020112146
Pubmed ID
Authors

Marialaura Bonaccio, Chiara Cerletti, Licia Iacoviello, Giovanni de Gaetano

Abstract

Low-grade chronic inflammation is an underlying pathophysiological mechanism linking risk factors and/or metabolic disorders to increased risk of chronic degenerative disease. A meat-based pattern, as the Western type diet, is positively linked to higher levels of some important biomarkers of inflammation, such as C-reactive protein (CRP), interleukin-6 and fibrinogen. Conversely, a Mediterranean-like eating behavior is associated with lower degree of these biomarkers thus suggesting an anti-inflammatory action of its main food components. This chapter goes through the most important investigations addressing the relationship between dietary habits and sub-clinical inflammation. Attention was focussed on the findings from the MOLI-SANI study: this is a large prospective cohort study that recruited 24,325 men and women from the general population of the Molise Region, a Southern Italian area, with the aim of investigating genetic and environmental risk/protection factors for cardiovascular and tumor disease. For the first time, the MOLI-SANI study carefully investigated the Mediterranean diet as an environmental determinant of both platelet and white blood cell counts, starting from the hypothesis that a diet rich in healthy compounds could favorably influence the production and/or the clearance of these two cellular biomarkers of low-grade inflammation. Additionally, evidence from this large Italian cohort showed that a Mediterranean-like diet was closely associated with relatively lower values of glucose, lipids, CRP, blood pressure and 10-year cardiovascular risk, while the consumption of healthy foods with high rather than low content in antioxidant vitamins and phytochemicals was associated with lower blood pressure and CRP plasma levels at least in men.

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 63 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 19%
Student > Master 10 16%
Student > Ph. D. Student 8 13%
Researcher 6 9%
Student > Doctoral Student 5 8%
Other 8 13%
Unknown 15 23%
Readers by discipline Count As %
Medicine and Dentistry 24 38%
Nursing and Health Professions 11 17%
Biochemistry, Genetics and Molecular Biology 3 5%
Agricultural and Biological Sciences 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 3 5%
Unknown 19 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 204. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2017.
All research outputs
#61,878
of 13,199,565 outputs
Outputs from Endocrine, Metabolic & Immune Disorders - Drug Targets
#1
of 216 outputs
Outputs of similar age
#1,205
of 231,875 outputs
Outputs of similar age from Endocrine, Metabolic & Immune Disorders - Drug Targets
#1
of 11 outputs
Altmetric has tracked 13,199,565 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 216 research outputs from this source. They receive a mean Attention Score of 2.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,875 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.