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PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

Overview of attention for article published in Nature Communications, October 2017
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

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8 news outlets
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8 X users

Citations

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37 Dimensions

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67 Mendeley
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Title
PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies
Published in
Nature Communications, October 2017
DOI 10.1038/s41467-017-00802-2
Pubmed ID
Authors

Molly A. Hall, John Wallace, Anastasia Lucas, Dokyoon Kim, Anna O. Basile, Shefali S. Verma, Cathy A. McCarty, Murray H. Brilliant, Peggy L. Peissig, Terrie E. Kitchner, Anurag Verma, Sarah A. Pendergrass, Scott M. Dudek, Jason H. Moore, Marylyn D. Ritchie

Abstract

Genome-wide, imputed, sequence, and structural data are now available for exceedingly large sample sizes. The needs for data management, handling population structure and related samples, and performing associations have largely been met. However, the infrastructure to support analyses involving complexity beyond genome-wide association studies is not standardized or centralized. We provide the PLatform for the Analysis, Translation, and Organization of large-scale data (PLATO), a software tool equipped to handle multi-omic data for hundreds of thousands of samples to explore complexity using genetic interactions, environment-wide association studies and gene-environment interactions, phenome-wide association studies, as well as copy number and rare variant analyses. Using the data from the Marshfield Personalized Medicine Research Project, a site in the electronic Medical Records and Genomics Network, we apply each feature of PLATO to type 2 diabetes and demonstrate how PLATO can be used to uncover the complex etiology of common traits.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 67 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 22%
Student > Bachelor 8 12%
Student > Master 8 12%
Student > Ph. D. Student 7 10%
Student > Doctoral Student 5 7%
Other 9 13%
Unknown 15 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 15 22%
Medicine and Dentistry 10 15%
Agricultural and Biological Sciences 10 15%
Computer Science 4 6%
Business, Management and Accounting 2 3%
Other 8 12%
Unknown 18 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 March 2019.
All research outputs
#661,141
of 24,288,381 outputs
Outputs from Nature Communications
#11,368
of 51,787 outputs
Outputs of similar age
#14,498
of 332,474 outputs
Outputs of similar age from Nature Communications
#359
of 1,455 outputs
Altmetric has tracked 24,288,381 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 51,787 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 56.3. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,474 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 1,455 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.