Title |
Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in Tanzanian children aged 12–24 months
|
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Published in |
Malaria Journal, July 2009
|
DOI | 10.1186/1475-2875-8-163 |
Pubmed ID | |
Authors |
John PA Lusingu, Samwel Gesase, Salum Msham, Filbert Francis, Martha Lemnge, Misago Seth, Samwel Sembuche, Acleus Rutta, Daniel Minja, Method D Segeja, Samuel Bosomprah, Simon Cousens, Ramadhani Noor, Roma Chilengi, Pierre Druilhe |
Abstract |
Development and deployment of an effective malaria vaccine would complement existing malaria control measures. A blood stage malaria vaccine candidate, Merozoite Surface Protein-3 (MSP3), produced as a long synthetic peptide, has been shown to be safe in non-immune and semi-immune adults. A phase Ib dose-escalating study was conducted to assess the vaccine's safety and immunogenicity in children aged 12 to 24 months in Korogwe, Tanzania (ClinicalTrials.gov number: NCT00469651). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
India | 1 | 1% |
France | 1 | 1% |
Unknown | 80 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 15 | 18% |
Student > Ph. D. Student | 14 | 17% |
Researcher | 10 | 12% |
Student > Bachelor | 9 | 11% |
Student > Doctoral Student | 3 | 4% |
Other | 11 | 13% |
Unknown | 21 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 27% |
Agricultural and Biological Sciences | 14 | 17% |
Immunology and Microbiology | 6 | 7% |
Nursing and Health Professions | 5 | 6% |
Social Sciences | 3 | 4% |
Other | 10 | 12% |
Unknown | 23 | 28% |