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Transcriptional repression is epigenetically marked by H3K9 methylation during SV40 replication

Overview of attention for article published in Clinical Epigenetics, October 2014
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Title
Transcriptional repression is epigenetically marked by H3K9 methylation during SV40 replication
Published in
Clinical Epigenetics, October 2014
DOI 10.1186/1868-7083-6-21
Pubmed ID
Authors

Les Kallestad, Kendra Christensen, Emily Woods, Barry Milavetz

Abstract

We have recently shown that T-antigen binding to Site I results in the replication-dependent introduction of H3K9me1 into SV40 chromatin late in infection. Since H3K9me2 and H3K9me3 are also present late in infection, we determined whether their presence was also related to the status of ongoing transcription and replication. Transcription was either inhibited with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidizole (DRB) or stimulated with sodium butyrate and the effects on histone modifications early and late in infection determined. The role of DNA replication was determined by concomitant inhibition of replication with aphidicolin.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 35%
Student > Ph. D. Student 4 24%
Student > Doctoral Student 1 6%
Student > Master 1 6%
Professor > Associate Professor 1 6%
Other 1 6%
Unknown 3 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 47%
Agricultural and Biological Sciences 7 41%
Unknown 2 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2014.
All research outputs
#13,922,082
of 22,768,097 outputs
Outputs from Clinical Epigenetics
#701
of 1,243 outputs
Outputs of similar age
#130,813
of 260,282 outputs
Outputs of similar age from Clinical Epigenetics
#9
of 14 outputs
Altmetric has tracked 22,768,097 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,243 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,282 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.