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Rheumatoid arthritis seems to have DMARD treatment decision influenced by fibromyalgia

Overview of attention for article published in Revista Brasileira de Reumatologia (English Edition), September 2017
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52 Mendeley
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Title
Rheumatoid arthritis seems to have DMARD treatment decision influenced by fibromyalgia
Published in
Revista Brasileira de Reumatologia (English Edition), September 2017
DOI 10.1016/j.rbre.2017.01.004
Pubmed ID
Authors

Rafael Mendonça da Silva Chakr, Claiton Brenol, Aline Ranzolin, Amanda Bernardes, Ana Paula Dalosto, Giovani Ferrari, Stephanie Scalco, Vanessa Olszewski, Charles Kohem, Odirlei Monticielo, João Carlos T. Brenol, Ricardo M. Xavier

Abstract

To compare DMARD use in patients with and without FM over time, including overtreatment and undertreatment rates in both groups. A prospective cohort study with patients attending an RA outpatient clinic was conducted. Participants were consecutively recruited between March 2006 and June 2007 and were followed through December 2013. Data on DMARD use (prevalences, doses and escalation rates), DAS28, HAQ and radiographic progression were compared among RA patients with FM and without FM. Mistreatment clinical scenarios were allegedly identified and compared between groups. 256 RA patients (32 with FM) were followed for 6.2±2.0 (mean±SD) years comprising 2986 visits. At baseline, RA duration was 11.1±7.4 years. DAS28 and HAQ were greater in RA with FM group, and were closer to RA without FM group towards the end. RA patients with FM used higher doses of tricyclic antidepressants, leflunomide and prednisone, and lower doses of methotrexate. When compared to RA patients without FM, participants with RA and FM used more often tricyclic antidepressants, leflunomide, prednisone, continuous analgesics and less often methotrexate. Groups presented similar 7-year biologic-free survival, and radiographic progression-free survival in Cox regression. RA patients with FM had greater proportions of visits in mistreatment scenarios when compared to RA patients without FM (28.4 vs. 19.8%, p<0.001). RA patients with FM used more leflunomide and prednisone, and RA mistreatment was more frequent in FM patients. Certainly, RA patients with FM will benefit from a personalized T2T strategy, including ultrasound (when suitable) and proper FM treatment.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 21%
Student > Master 8 15%
Student > Postgraduate 7 13%
Student > Doctoral Student 5 10%
Student > Bachelor 4 8%
Other 8 15%
Unknown 9 17%
Readers by discipline Count As %
Medicine and Dentistry 18 35%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Nursing and Health Professions 4 8%
Agricultural and Biological Sciences 4 8%
Biochemistry, Genetics and Molecular Biology 2 4%
Other 9 17%
Unknown 11 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 November 2017.
All research outputs
#7,798,989
of 13,535,469 outputs
Outputs from Revista Brasileira de Reumatologia (English Edition)
#22
of 61 outputs
Outputs of similar age
#155,177
of 313,617 outputs
Outputs of similar age from Revista Brasileira de Reumatologia (English Edition)
#2
of 3 outputs
Altmetric has tracked 13,535,469 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 61 research outputs from this source. They receive a mean Attention Score of 3.1. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,617 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.