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A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis

Overview of attention for article published in Trends in Pharmacological Sciences, December 2014
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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6 X users

Citations

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152 Dimensions

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255 Mendeley
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Title
A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis
Published in
Trends in Pharmacological Sciences, December 2014
DOI 10.1016/j.tips.2014.09.011
Pubmed ID
Authors

Olivia F. O’Leary, John F. Cryan

Abstract

Adult hippocampal neurogenesis is implicated in antidepressant action, stress responses, and cognitive functioning. The hippocampus is functionally segregated along its longitudinal axis into dorsal (dHi) and ventral (vHi) regions in rodents, and analogous posterior and anterior regions in primates, whereby the vHi preferentially regulates stress and anxiety, while the dHi preferentially regulates spatial learning and memory. Given the role of neurogenesis in functions preferentially regulated by the dHi or vHi, it is plausible that neurogenesis is preferentially regulated in either the dHi or vHi depending upon the stimulus. We appraise here the literature on the effects of stress and antidepressants on neurogenesis along the hippocampal longitudinal axis and explore whether preferential regulation of neurogenesis in the vHi/anterior hippocampus contributes to stress resilience and antidepressant action.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 255 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
France 1 <1%
Unknown 251 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 62 24%
Student > Bachelor 43 17%
Student > Master 31 12%
Researcher 24 9%
Student > Doctoral Student 22 9%
Other 41 16%
Unknown 32 13%
Readers by discipline Count As %
Neuroscience 79 31%
Agricultural and Biological Sciences 49 19%
Medicine and Dentistry 26 10%
Biochemistry, Genetics and Molecular Biology 17 7%
Psychology 16 6%
Other 19 7%
Unknown 49 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2015.
All research outputs
#6,774,148
of 22,769,322 outputs
Outputs from Trends in Pharmacological Sciences
#1,073
of 2,281 outputs
Outputs of similar age
#94,500
of 361,391 outputs
Outputs of similar age from Trends in Pharmacological Sciences
#15
of 23 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 2,281 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 361,391 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.