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First intraindividual comparison of contrast-enhanced MRI, FET- and DOTATOC- PET in patients with intracranial meningiomas

Overview of attention for article published in Radiation Oncology, November 2017
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Title
First intraindividual comparison of contrast-enhanced MRI, FET- and DOTATOC- PET in patients with intracranial meningiomas
Published in
Radiation Oncology, November 2017
DOI 10.1186/s13014-017-0913-x
Pubmed ID
Authors

Jan Oliver Dittmar, Clemens Kratochwil, Anne Dittmar, Thomas Welzel, Daniel Habermehl, Stefan Rieken, Frederik L. Giesel, Uwe Haberkorn, Jürgen Debus, Stephanie E. Combs

Abstract

For irradiation treatment planning of meningiomas the use of PET-scans is well established. The most frequently used tracers are either based on amino acids or the somatostatin receptor ligand DOTATOC. Since up to now no inter-institutionally accepted standard PET-tracer has been defined, the aim of this study was to evaluate the influence of these different types of PET-tracers on the GTV-definition. Twenty-one patients suffering from intracranial meningiomas underwent CT, MRI, FET- and DOTATOC-PET. First, tumour extension was delineated after image-fusion of CT and MRI (GTVCT/MRI). Then distinct GTVs based either on FET- or DOTATOC-PET were contoured and compared with each other as well with GTVCT/MRI. Every tumour showed typical enhancement of DOTATOC, but two meningiomas remained FET-negative. The mean relative overlap volume of GTVFET and GTVDOTATOC was only 41.9% and there was a significantly stronger correlation between GTVCT/MRI and GTVDOTATOC than between GTVCT/MRI and GTVFET . Further investigations are necessary to clarify the minor conformity of DOTATOC- and FET-PET in meningiomas. Because of the receptor targeting, DOTATOC is known to be more specific for meningiomas and will remain the standard in our institution with the known limitation in areas nearby the pituitary gland.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 15%
Other 3 11%
Student > Bachelor 3 11%
Researcher 3 11%
Student > Master 3 11%
Other 1 4%
Unknown 10 37%
Readers by discipline Count As %
Medicine and Dentistry 11 41%
Neuroscience 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Agricultural and Biological Sciences 1 4%
Nursing and Health Professions 1 4%
Other 2 7%
Unknown 9 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2018.
All research outputs
#14,084,031
of 23,007,887 outputs
Outputs from Radiation Oncology
#763
of 2,072 outputs
Outputs of similar age
#177,019
of 330,777 outputs
Outputs of similar age from Radiation Oncology
#11
of 27 outputs
Altmetric has tracked 23,007,887 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,072 research outputs from this source. They receive a mean Attention Score of 2.7. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,777 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.