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PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment

Overview of attention for article published in Molecular Cancer, November 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

news
1 news outlet
twitter
2 X users
patent
1 patent
peer_reviews
1 peer review site
facebook
1 Facebook page

Citations

dimensions_citation
43 Dimensions

Readers on

mendeley
73 Mendeley
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Title
PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment
Published in
Molecular Cancer, November 2014
DOI 10.1186/1476-4598-13-247
Pubmed ID
Authors

Carlo Cenciarelli, Hany ES Marei, Manuela Zonfrillo, Pasquale Pierimarchi, Emanuela Paldino, Patrizia Casalbore, Armando Felsani, Angelo Luigi Vescovi, Giulio Maira, Annunziato Mangiola

Abstract

Cancer stem cells (CSC) represent a rare fraction of cancer cells characterized by resistance to chemotherapy and radiation, therefore nowadays there is great need to develop new targeted therapies for brain tumors and our study aim to target pivotal transmembrane receptors such as Notch, EGFR and PDGFR, which are already under investigation in clinical trials setting for the treatment of Glioblastoma Multiforme (GBM).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Unknown 72 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Researcher 9 12%
Student > Bachelor 7 10%
Student > Master 6 8%
Student > Postgraduate 5 7%
Other 11 15%
Unknown 19 26%
Readers by discipline Count As %
Medicine and Dentistry 14 19%
Agricultural and Biological Sciences 13 18%
Biochemistry, Genetics and Molecular Biology 12 16%
Neuroscience 3 4%
Engineering 2 3%
Other 10 14%
Unknown 19 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2022.
All research outputs
#2,297,413
of 25,374,917 outputs
Outputs from Molecular Cancer
#130
of 1,918 outputs
Outputs of similar age
#26,552
of 276,417 outputs
Outputs of similar age from Molecular Cancer
#1
of 39 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,918 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,417 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.