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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy
|
|---|---|
| Published in |
Frontiers in immunology, October 2017
|
| DOI | 10.3389/fimmu.2017.01228 |
| Pubmed ID | |
| Authors |
Sohini Roy, Arup K. Bag, Rakesh K. Singh, James E. Talmadge, Surinder K. Batra, Kaustubh Datta |
| Abstract |
Neuropilins (NRPs) are non-tyrosine kinase cell surface glycoproteins expressed in all vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 (NRP1) and neuropilin-2 (NRP2), mainly act as coreceptors for class III Semaphorins and for members of the vascular endothelial growth factor family of molecules and are widely known for their role in a wide array of physiological processes, such as cardiovascular, neuronal development and patterning, angiogenesis, lymphangiogenesis, as well as various clinical disorders. Intriguingly, additional roles for NRPs occur with myeloid and lymphoid cells, in normal physiological as well as different pathological conditions, including cancer, immunological disorders, and bone diseases. However, little is known concerning the molecular pathways that govern these functions. In addition, NRP1 expression has been characterized in different immune cellular phenotypes including macrophages, dendritic cells, and T cell subsets, especially regulatory T cell populations. By contrast, the functions of NRP2 in immune cells are less well known. In this review, we briefly summarize the genomic organization, structure, and binding partners of the NRPs and extensively discuss the recent advances in their role and function in different immune cell subsets and their clinical implications. |
X Demographics
The data shown below were collected from the profiles of 21 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 5 | 24% |
| United States | 2 | 10% |
| Bolivia, Plurinational State of | 1 | 5% |
| South Africa | 1 | 5% |
| Italy | 1 | 5% |
| Switzerland | 1 | 5% |
| Unknown | 10 | 48% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 86% |
| Practitioners (doctors, other healthcare professionals) | 3 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 207 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 207 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 17% |
| Student > Ph. D. Student | 25 | 12% |
| Student > Bachelor | 18 | 9% |
| Student > Doctoral Student | 17 | 8% |
| Student > Master | 16 | 8% |
| Other | 21 | 10% |
| Unknown | 75 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 37 | 18% |
| Medicine and Dentistry | 23 | 11% |
| Immunology and Microbiology | 23 | 11% |
| Agricultural and Biological Sciences | 17 | 8% |
| Chemistry | 6 | 3% |
| Other | 20 | 10% |
| Unknown | 81 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2024.
All research outputs
#2,831,515
of 26,047,917 outputs
Outputs from Frontiers in immunology
#2,940
of 32,777 outputs
Outputs of similar age
#51,178
of 337,135 outputs
Outputs of similar age from Frontiers in immunology
#62
of 540 outputs
Altmetric has tracked 26,047,917 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 32,777 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 337,135 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 540 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.