↓ Skip to main content

The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females

Overview of attention for article published in BMC Cancer, November 2014
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
1 blog
twitter
96 X users
facebook
1 Facebook page

Citations

dimensions_citation
38 Dimensions

Readers on

mendeley
38 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The molecular significance of methylated BRCA1 promoter in white blood cells of cancer-free females
Published in
BMC Cancer, November 2014
DOI 10.1186/1471-2407-14-830
Pubmed ID
Authors

Nisreen Al-Moghrabi, Asmaa Nofel, Nujoud Al-Yousef, Safia Madkhali, Suad M Bin Amer, Ayodele Alaiya, Zakia Shinwari, Taher Al-Tweigeri, Bedri Karakas, Asma Tulbah, Abdelilah Aboussekhra

Abstract

BRCA1 promoter methylation has been detected in DNA from peripheral blood cells of both breast cancer patients and cancer-free females. However, the pathological significance of this epigenetic change in white blood cells (WBC) remains an open question. In this study, we hypothesized that if constitutional BRCA1 methylation reflects an elevated risk for developing breast cancer (BC), WBC that harbor methylated BRCA1 in both cancer-free females and BC patients should exhibit similar molecular changes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 96 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 2 5%
Unknown 36 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 26%
Student > Master 6 16%
Researcher 4 11%
Student > Doctoral Student 3 8%
Student > Bachelor 2 5%
Other 6 16%
Unknown 7 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 29%
Medicine and Dentistry 7 18%
Agricultural and Biological Sciences 5 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Engineering 2 5%
Other 2 5%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 79. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2018.
All research outputs
#533,602
of 25,292,646 outputs
Outputs from BMC Cancer
#64
of 8,918 outputs
Outputs of similar age
#6,333
of 373,295 outputs
Outputs of similar age from BMC Cancer
#2
of 177 outputs
Altmetric has tracked 25,292,646 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,918 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 373,295 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 177 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.