Because neural stemness is the key feature of cancer (tumorigenic) cells, therefore, non-neural genes are usually tumor suppressors. Sustained inhibition of these types of genes will cause or promote cancer. See the dark side of PD-1 inhibition. https:/
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RT @Peerus: Inhibiting the protein PD-1 can activate T cells that trigger immune responses against tumour cells. But it emerges that, in mi…
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Inhibiting the protein PD-1 can activate T cells that trigger immune responses against tumour cells. But it emerges that, in mice, this immunotherapy exacerbates a cancer that involves the T cells themselves. Source : @nature https://t.co/mpxENnat9e #rese
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RT @NatureJapan: 祝:本庶佑先生ノーベル医学・生理学賞受賞 関連記事紹介【チェックポイント因子はリンパ腫を抑制する | Nature | Nature Research】 https://t.co/ATaw9u3v71