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Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein

Overview of attention for article published in Virology Journal, November 2014
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Mentioned by

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2 tweeters

Citations

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5 Dimensions

Readers on

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12 Mendeley
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Title
Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein
Published in
Virology Journal, November 2014
DOI 10.1186/s12985-014-0191-2
Pubmed ID
Authors

Adam B Shapiro, Ning Gao, Nichole O’Connell, Jun Hu, Jason Thresher, Rong-Fang Gu, Ross Overman, Ian M Hardern, Graham G Sproat

Abstract

There are no approved small molecule drug therapies for human respiratory syncytial virus (hRSV), a cause of morbidity and mortality in at-risk newborns, the immunocompromised, and the elderly. We have investigated as a potential novel hRSV drug target the protein-protein interaction between the C-terminus of the viral phosphoprotein (P) and the viral nucleocapsid protein (N), components of the ribonucleoprotein complex that contains, replicates, and transcribes the viral RNA genome. Earlier work by others established that the 9 C-terminal residues of P are necessary and sufficient for binding to N.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 33%
Student > Master 3 25%
Researcher 2 17%
Student > Doctoral Student 1 8%
Unknown 2 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 25%
Medicine and Dentistry 2 17%
Immunology and Microbiology 1 8%
Psychology 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Other 1 8%
Unknown 3 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2014.
All research outputs
#2,325,514
of 4,531,279 outputs
Outputs from Virology Journal
#748
of 1,275 outputs
Outputs of similar age
#69,335
of 139,044 outputs
Outputs of similar age from Virology Journal
#47
of 56 outputs
Altmetric has tracked 4,531,279 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,275 research outputs from this source. They receive a mean Attention Score of 3.2. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 139,044 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.