Title |
In vitro growth of Plasmodium falciparum in neonatal blood
|
---|---|
Published in |
Malaria Journal, November 2014
|
DOI | 10.1186/1475-2875-13-436 |
Pubmed ID | |
Authors |
Ulrich Sauerzopf, Yabo J Honkpehedji, Ayôla A Adgenika, Elianne N Feugap, Ghyslain Mombo Ngoma, Jean-Rodolphe Mackanga, Felix Lötsch, Marguerite M Loembe, Peter G Kremsner, Benjamin Mordmüller, Michael Ramharter |
Abstract |
Children below the age of six months suffer less often from malaria than older children in sub-Saharan Africa. This observation is commonly attributed to the persistence of foetal haemoglobin (HbF), which is considered not to permit growth of Plasmodium falciparum and therefore providing protection against malaria. Since this concept has recently been challenged, this study evaluated the effect of HbF erythrocytes and maternal plasma on in vitro parasite growth of P. falciparum in Central African Gabon. |
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Members of the public | 2 | 100% |
Mendeley readers
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Demographic breakdown
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Unspecified | 4 | 10% |
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