Chapter title |
Pathway Design, Engineering, and Optimization
|
---|---|
Chapter number | 12 |
Book title |
Synthetic Biology – Metabolic Engineering
|
Published in |
Advances in biochemical engineering biotechnology, September 2016
|
DOI | 10.1007/10_2016_12 |
Pubmed ID | |
Book ISBNs |
978-3-31-955317-7, 978-3-31-955318-4
|
Authors |
Garcia-Ruiz, Eva, HamediRad, Mohammad, Zhao, Huimin, Eva Garcia-Ruiz, Mohammad HamediRad, Huimin Zhao |
Abstract |
The microbial metabolic versatility found in nature has inspired scientists to create microorganisms capable of producing value-added compounds. Many endeavors have been made to transfer and/or combine pathways, existing or even engineered enzymes with new function to tractable microorganisms to generate new metabolic routes for drug, biofuel, and specialty chemical production. However, the success of these pathways can be impeded by different complications from an inherent failure of the pathway to cell perturbations. Pursuing ways to overcome these shortcomings, a wide variety of strategies have been developed. This chapter will review the computational algorithms and experimental tools used to design efficient metabolic routes, and construct and optimize biochemical pathways to produce chemicals of high interest. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 19% |
Other | 4 | 9% |
Student > Ph. D. Student | 4 | 9% |
Student > Master | 4 | 9% |
Student > Bachelor | 2 | 5% |
Other | 4 | 9% |
Unknown | 17 | 40% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 12 | 28% |
Agricultural and Biological Sciences | 6 | 14% |
Engineering | 3 | 7% |
Environmental Science | 2 | 5% |
Chemistry | 1 | 2% |
Other | 1 | 2% |
Unknown | 18 | 42% |