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Synthetic Biology – Metabolic Engineering

Overview of attention for book
Cover of 'Synthetic Biology – Metabolic Engineering'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 2 Synergizing 13C Metabolic Flux Analysis and Metabolic Engineering for Biochemical Production
  3. Altmetric Badge
    Chapter 3 Synthetic Biology of Polyhydroxyalkanoates (PHA)
  4. Altmetric Badge
    Chapter 8 Promoter and Terminator Discovery and Engineering
  5. Altmetric Badge
    Chapter 9 Engineering Biomolecular Switches for Dynamic Metabolic Control
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    Chapter 12 Pathway Design, Engineering, and Optimization
  7. Altmetric Badge
    Chapter 13 Synthetic Biology for Cell-Free Biosynthesis: Fundamentals of Designing Novel In Vitro Multi-Enzyme Reaction Networks
  8. Altmetric Badge
    Chapter 14 Xenobiology: State-of-the-Art, Ethics, and Philosophy of New-to-Nature Organisms
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    Chapter 21 Corynebacterium glutamicum for Sustainable Bioproduction: From Metabolic Physiology to Systems Metabolic Engineering
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    Chapter 22 Engineering and Evolution of Saccharomyces cerevisiae to Produce Biofuels and Chemicals
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    Chapter 37 Orthogonal Protein Translation Using Pyrrolysyl-tRNA Synthetases for Single- and Multiple-Noncanonical Amino Acid Mutagenesis
Attention for Chapter 9: Engineering Biomolecular Switches for Dynamic Metabolic Control
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Citations

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9 Dimensions

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32 Mendeley
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Chapter title
Engineering Biomolecular Switches for Dynamic Metabolic Control
Chapter number 9
Book title
Synthetic Biology – Metabolic Engineering
Published in
Advances in biochemical engineering biotechnology, June 2016
DOI 10.1007/10_2016_9
Pubmed ID
27277392
Book ISBNs
978-3-31-955317-7, 978-3-31-955318-4
Authors

Ma, Cheng-Wei, Zhou, Li-Bang, Zeng, An-Ping, Cheng-Wei Ma, Li-Bang Zhou, An-Ping Zeng

Abstract

Living organisms have been exploited as production hosts for a large variety of compounds. To improve the efficiency of bioproduction, metabolic pathways in an organism are usually manipulated by various genetic modifications. However, bottlenecks during the conversion of substrate to a desired product may result from cellular regulations at different levels. Dynamic regulation of metabolic pathways according to the need of cultivation process is therefore essential for developing effective bioprocesses, but represents a major challenge in metabolic engineering and synthetic biology. To this end, switchable biomolecules which can sense the intracellular concentrations of metabolites with different response types and dynamic ranges are of great interest. This chapter summarizes recent progress in the development of biomolecular switches and their applications for improvement of bioproduction via dynamic control of metabolic fluxes. Further studies of bioswitches and their applications in industrial strain development are also discussed.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
China 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 31%
Researcher 4 13%
Student > Master 4 13%
Student > Postgraduate 3 9%
Student > Bachelor 3 9%
Other 5 16%
Unknown 3 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 38%
Agricultural and Biological Sciences 8 25%
Chemical Engineering 2 6%
Engineering 2 6%
Mathematics 1 3%
Other 2 6%
Unknown 5 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2018.
All research outputs
#14,793,338
of 23,666,309 outputs
Outputs from Advances in biochemical engineering biotechnology
#104
of 217 outputs
Outputs of similar age
#196,855
of 345,361 outputs
Outputs of similar age from Advances in biochemical engineering biotechnology
#3
of 4 outputs
Altmetric has tracked 23,666,309 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 217 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,361 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.

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