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Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease

Overview of attention for article published in Revista da Sociedade Brasileira de Medicina Tropical, September 2017
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1 tweeter

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Title
Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease
Published in
Revista da Sociedade Brasileira de Medicina Tropical, September 2017
DOI 10.1590/0037-8682-0025-2017
Pubmed ID
Authors

Matheus Barbosa de Miranda, Adriene Siqueira de Melo, Mariana Silva Almeida, Silvia Martins Marinho, Wilson Oliveira Junior, Yara de Miranda Gomes

Abstract

Elucidating the molecules involved in the inflammatory process of chronic Chagas disease may allow identification of treatment targets. The ex vivo phenotypic expression of chemokine receptors CCR1, CCR3, CCR4, CCR5, CXCR2, CXCR3, CXCR4, and CXCR5 on the CD4+ and CD8+ T-cells of patients with chronic Chagas cardiomyopathy of varying severity was evaluated using flow cytometry. Differential expression of CD4+CCR3+ and CD8+CCR4+ T-cells was observed in patients with mild cardiac involvement compared, respectively, with patients with severe cardiac and asymptomatic forms of Chagas disease. These receptors are possibly involved in the pathogenesis of chronic Chagas cardiomyopathy.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 21%
Researcher 3 16%
Student > Master 2 11%
Student > Doctoral Student 1 5%
Lecturer 1 5%
Other 5 26%
Unknown 3 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 21%
Immunology and Microbiology 4 21%
Medicine and Dentistry 2 11%
Engineering 2 11%
Social Sciences 1 5%
Other 3 16%
Unknown 3 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2017.
All research outputs
#10,024,210
of 12,527,863 outputs
Outputs from Revista da Sociedade Brasileira de Medicina Tropical
#77
of 216 outputs
Outputs of similar age
#275,771
of 384,053 outputs
Outputs of similar age from Revista da Sociedade Brasileira de Medicina Tropical
#27
of 63 outputs
Altmetric has tracked 12,527,863 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 216 research outputs from this source. They receive a mean Attention Score of 1.4. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 384,053 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.