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SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

Overview of attention for article published in Molecular Neurodegeneration, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

news
1 news outlet
twitter
3 tweeters
patent
3 patents
facebook
1 Facebook page

Citations

dimensions_citation
110 Dimensions

Readers on

mendeley
148 Mendeley
citeulike
1 CiteULike
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Title
SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease
Published in
Molecular Neurodegeneration, January 2014
DOI 10.1186/1750-1326-9-53
Pubmed ID
Authors

Ann Brinkmalm, Gunnar Brinkmalm, William G Honer, Lutz Frölich, Lucrezia Hausner, Lennart Minthon, Oskar Hansson, Anders Wallin, Henrik Zetterberg, Kaj Blennow, Annika Öhrfelt

Abstract

Synaptic degeneration is an early pathogenic event in Alzheimer's disease, associated with cognitive impairment and disease progression. Cerebrospinal fluid biomarkers reflecting synaptic integrity would be highly valuable tools to monitor synaptic degeneration directly in patients. We previously showed that synaptic proteins such as synaptotagmin and synaptosomal-associated protein 25 (SNAP-25) could be detected in pooled samples of cerebrospinal fluid, however these assays were not sensitive enough for individual samples.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 148 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Belgium 1 <1%
Unknown 146 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 39 26%
Student > Ph. D. Student 32 22%
Student > Master 14 9%
Student > Bachelor 10 7%
Student > Doctoral Student 9 6%
Other 20 14%
Unknown 24 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 18%
Neuroscience 27 18%
Medicine and Dentistry 25 17%
Biochemistry, Genetics and Molecular Biology 13 9%
Psychology 5 3%
Other 15 10%
Unknown 36 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2019.
All research outputs
#1,188,432
of 15,872,090 outputs
Outputs from Molecular Neurodegeneration
#67
of 644 outputs
Outputs of similar age
#24,122
of 307,920 outputs
Outputs of similar age from Molecular Neurodegeneration
#2
of 20 outputs
Altmetric has tracked 15,872,090 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 644 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,920 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.