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Nanocellulose reinforced gellan-gum hydrogels as potential biological substitutes for annulus fibrosus tissue regeneration

Overview of attention for article published in Nanomedicine: Nanotechnology, Biology and Medicine, April 2018
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

twitter
5 tweeters

Citations

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11 Dimensions

Readers on

mendeley
48 Mendeley
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Title
Nanocellulose reinforced gellan-gum hydrogels as potential biological substitutes for annulus fibrosus tissue regeneration
Published in
Nanomedicine: Nanotechnology, Biology and Medicine, April 2018
DOI 10.1016/j.nano.2017.11.011
Pubmed ID
Authors

Diana R. Pereira, Joana Silva-Correia, Joaquim M. Oliveira, Rui L. Reis, Abhay Pandit, Manus J. Biggs

Abstract

Intervertebral disc (IVD) degeneration is related to both structural damage and aging. Annulus fibrosus (AF) defects such as annular tears, herniation and discectomy require novel strategies to functionally repair AF tissue. An ideal construct will repair the AF by providing physical and biological support and by facilitating regeneration. The present strategy proposes a gellan gum-based construct reinforced with cellulose nanocrystals (nCell) as a biological self-gelling AF substitute. Nanocomposite hydrogels were fabricated and characterized for their swelling capacity and stability and physico-chemical properties. Rheological evaluation on the nanocomposites demonstrated the GGMA reinforcement with nCell and thus matrix entanglements with higher stiffness upon ionic crosslinking. Compressive mechanical tests demonstrate values close to those of the human AF tissue. Furthermore, cell culture studies by means of gel loading with bovine AF cells indicated that the construct promoted cell viability and a physiologically relevant morphology for up to fourteen days in vitro.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 19%
Unspecified 7 15%
Student > Master 7 15%
Researcher 6 13%
Student > Doctoral Student 6 13%
Other 13 27%
Readers by discipline Count As %
Engineering 10 21%
Unspecified 9 19%
Materials Science 7 15%
Agricultural and Biological Sciences 6 13%
Chemistry 6 13%
Other 10 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2018.
All research outputs
#3,187,725
of 12,585,503 outputs
Outputs from Nanomedicine: Nanotechnology, Biology and Medicine
#184
of 1,027 outputs
Outputs of similar age
#114,868
of 386,055 outputs
Outputs of similar age from Nanomedicine: Nanotechnology, Biology and Medicine
#6
of 28 outputs
Altmetric has tracked 12,585,503 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,027 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 386,055 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.