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Early emergency department treatment of acute asthma with systemic corticosteroids

Overview of attention for article published in Cochrane database of systematic reviews, January 2001
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (77th percentile)

Mentioned by

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2 tweeters
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

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356 Dimensions

Readers on

mendeley
221 Mendeley
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1 CiteULike
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Title
Early emergency department treatment of acute asthma with systemic corticosteroids
Published in
Cochrane database of systematic reviews, January 2001
DOI 10.1002/14651858.cd002178
Pubmed ID
Authors

Brian H Rowe, Carol Spooner, Francine Ducharme, Jennifer Bretzlaff, Gary Bota

Abstract

The airway edema and secretions associated with acute asthma are most effectively treated with anti-inflammatories such as corticosteroids delivered by inhaled, oral, intravenous or intra-muscular routes. There is an unresolved debate about the use of systemic corticorticoids in the early treatment of acute asthma for emergency department patients. To determine the benefit of treating patients with acute asthma with systemic corticosteroids within an hour of presenting to the emergency department (ED). Randomised controlled trials were identified from the Cochrane Airways Group Asthma Register. Primary authors and content experts were contacted to identify eligible studies. Bibliographies from included studies and known reviews were searched. Only randomised controlled trials (RCTs) or quasi-randomised trials were eligible for inclusion. Studies were included if patients presenting to the ED with acute asthma were treated with IV/IM or oral corticosteroids (CS) vs. placebo within 1 hour of arrival and either admission rate or pulmonary function results were reported. Trial selection, data extraction and quality assessment were carried out independently by two reviewers, and confirmed with corresponding authors. Twelve studies involving 863 patients (435 corticosteroids; 428 placebo) were included. Early use of CS for acute asthma in the ED significantly reduced admission rates (N = 11; pooled OR: 0.40, 95% CI: 0.21 to 0.78). This would correspond with a number needed to treat of 8 (95% CI: 5 to 21). This benefit was more pronounced for those not receiving systemic CS prior to ED presentation (N = 7; OR: 0.37, 95% CI: 0.19 to 0.70) and those with more severe asthma (N = 7; OR: 0.35, 95% CI: 0.21 to 0.59). Oral CS therapy in children was particularly effective (N = 3; OR: 0.24, 95% CI: 0.11 to 0.53); no trials in adults used the oral route. Side effects were not significantly different between corticosteroid treatments and placebo. A further search was conducted in September 2000 which did not yield any further trials. Use of corticosteroids within 1 hour of presentation to an ED significantly reduces the need for hospital admission in patients with acute asthma. Benefits appear greatest in patients with more severe asthma, and those not currently receiving steroids. Children appear to respond well to oral steroids.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 221 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
United Kingdom 2 <1%
Canada 1 <1%
Japan 1 <1%
Spain 1 <1%
Unknown 212 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 35 16%
Researcher 35 16%
Student > Master 34 15%
Student > Postgraduate 21 10%
Other 21 10%
Other 48 22%
Unknown 27 12%
Readers by discipline Count As %
Medicine and Dentistry 137 62%
Nursing and Health Professions 14 6%
Pharmacology, Toxicology and Pharmaceutical Science 12 5%
Agricultural and Biological Sciences 7 3%
Biochemistry, Genetics and Molecular Biology 4 2%
Other 11 5%
Unknown 36 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2019.
All research outputs
#3,691,981
of 14,619,289 outputs
Outputs from Cochrane database of systematic reviews
#6,378
of 11,034 outputs
Outputs of similar age
#66,921
of 300,386 outputs
Outputs of similar age from Cochrane database of systematic reviews
#181
of 252 outputs
Altmetric has tracked 14,619,289 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 11,034 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.5. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,386 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 252 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.