Title |
RNA-seq analysis of broiler liver transcriptome reveals novel responses to high ambient temperature
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1084 |
Pubmed ID | |
Authors |
Derrick J Coble, Damarius Fleming, Michael E Persia, Chris M Ashwell, Max F Rothschild, Carl J Schmidt, Susan J Lamont |
Abstract |
In broilers, high ambient temperature can result in reduced feed consumption, digestive inefficiency, impaired metabolism, and even death. The broiler sector of the U.S. poultry industry incurs approximately $52 million in heat-related losses annually. The objective of this study is to characterize the effects of cyclic high ambient temperature on the transcriptome of a metabolically active organ, the liver. This study provides novel insight into the effects of high ambient temperature on metabolism in broilers, because it is the first reported RNA-seq study to characterize the effect of heat on the transcriptome of a metabolic-related tissue. This information provides a platform for future investigations to further elucidate physiologic responses to high ambient temperature and seek methods to ameliorate the negative impacts of heat. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 25% |
France | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 3 | 75% |
Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 2% |
Unknown | 65 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 17 | 26% |
Student > Master | 11 | 17% |
Researcher | 10 | 15% |
Student > Doctoral Student | 3 | 5% |
Lecturer | 3 | 5% |
Other | 6 | 9% |
Unknown | 16 | 24% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 25 | 38% |
Biochemistry, Genetics and Molecular Biology | 6 | 9% |
Veterinary Science and Veterinary Medicine | 4 | 6% |
Immunology and Microbiology | 3 | 5% |
Medicine and Dentistry | 3 | 5% |
Other | 5 | 8% |
Unknown | 20 | 30% |