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Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia

Overview of attention for article published in BMC Musculoskeletal Disorders, December 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (59th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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2 tweeters
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1 Facebook page

Readers on

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47 Mendeley
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Title
Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia
Published in
BMC Musculoskeletal Disorders, December 2014
DOI 10.1186/1471-2474-15-422
Pubmed ID
Authors

Benjamin Gantenbein, Elena Calandriello, Karin Wuertz-Kozak, Lorin M Benneker, Marius JB Keel, Samantha CW Chan

Abstract

Notochordal cells (NC) remain in the focus of research for regenerative therapy for the degenerated intervertebral disc (IVD) due to their progenitor status. Recent findings suggested their regenerative action on more mature disc cells, presumably by the secretion of specific factors, which has been described as notochordal cell conditioned medium (NCCM). The aim of this study was to determine NC culture conditions (2D/3D, fetal calf serum, oxygen level) that lead to significant IVD cell activation in an indirect co-culture system under normoxia and hypoxia (2% oxygen).

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
Spain 1 2%
Singapore 1 2%
Unknown 43 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 21%
Researcher 10 21%
Student > Master 7 15%
Student > Bachelor 5 11%
Student > Doctoral Student 3 6%
Other 7 15%
Unknown 5 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 26%
Medicine and Dentistry 10 21%
Biochemistry, Genetics and Molecular Biology 7 15%
Engineering 7 15%
Materials Science 2 4%
Other 2 4%
Unknown 7 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2014.
All research outputs
#2,233,624
of 5,036,026 outputs
Outputs from BMC Musculoskeletal Disorders
#790
of 1,695 outputs
Outputs of similar age
#68,986
of 175,645 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#35
of 76 outputs
Altmetric has tracked 5,036,026 research outputs across all sources so far. This one has received more attention than most of these and is in the 54th percentile.
So far Altmetric has tracked 1,695 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 175,645 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
We're also able to compare this research output to 76 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.