↓ Skip to main content

Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade

Overview of attention for article published in Journal for Immunotherapy of Cancer, December 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
1 X user
patent
4 patents
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

dimensions_citation
194 Dimensions

Readers on

mendeley
215 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade
Published in
Journal for Immunotherapy of Cancer, December 2014
DOI 10.1186/s40425-014-0042-0
Pubmed ID
Authors

Evan J Lipson, Victor E Velculescu, Theresa S Pritchard, Mark Sausen, Drew M Pardoll, Suzanne L Topalian, Luis A Diaz

Abstract

Assessment of therapeutic activity of drugs blocking immune checkpoints such as CTLA-4 and PD-1/PD-L1 can be challenging, as tumors may seem to enlarge or appear anew before regressing, due to intratumoral inflammation. We assessed whether circulating tumor DNA (ctDNA) levels could serve as an early indicator of true changes in tumor burden in patients undergoing treatment with these agents.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 215 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Netherlands 1 <1%
Ireland 1 <1%
Switzerland 1 <1%
Unknown 211 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 48 22%
Student > Ph. D. Student 35 16%
Other 23 11%
Student > Bachelor 20 9%
Student > Master 17 8%
Other 34 16%
Unknown 38 18%
Readers by discipline Count As %
Medicine and Dentistry 73 34%
Biochemistry, Genetics and Molecular Biology 41 19%
Agricultural and Biological Sciences 32 15%
Immunology and Microbiology 3 1%
Engineering 3 1%
Other 17 8%
Unknown 46 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 28. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#1,412,382
of 25,608,265 outputs
Outputs from Journal for Immunotherapy of Cancer
#355
of 3,470 outputs
Outputs of similar age
#18,291
of 362,024 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#1
of 63 outputs
Altmetric has tracked 25,608,265 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,470 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.7. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,024 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.