Title |
RNA-seq analysis reveals significant transcriptome changes in turbot (Scophthalmus maximus) suffering severe enteromyxosis
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Published in |
BMC Genomics, December 2014
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DOI | 10.1186/1471-2164-15-1149 |
Pubmed ID | |
Authors |
Diego Robledo, Paolo Ronza, Peter W Harrison, Ana Paula Losada, Roberto Bermúdez, Belén G Pardo, María José Redondo, Ariadna Sitjà-Bobadilla, María Isabel Quiroga, Paulino Martínez |
Abstract |
Enteromyxosis caused by the intestinal myxozoan parasite Enteromyxum scophthalmi is a serious threat for turbot (Scophthalmus maximus, L.) aquaculture, causing severe catarrhal enteritis leading to a cachectic syndrome, with no therapeutic options available. There are still many aspects of host-parasite interaction and disease pathogenesis that are yet to be elucidated, and to date, no analysis of the transcriptomic changes induced by E. scophthalmi in turbot organs has been conducted. In this study, RNA-seq technology was applied to head kidney, spleen and pyloric caeca of severely infected turbot with the aim of furthering our understanding of the pathogenetic mechanisms and turbot immune response against enteromyxosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 1% |
Unknown | 77 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 21 | 27% |
Student > Ph. D. Student | 15 | 19% |
Student > Master | 8 | 10% |
Student > Bachelor | 8 | 10% |
Student > Doctoral Student | 5 | 6% |
Other | 9 | 12% |
Unknown | 12 | 15% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 8 | 10% |
Veterinary Science and Veterinary Medicine | 6 | 8% |
Medicine and Dentistry | 3 | 4% |
Neuroscience | 2 | 3% |
Other | 5 | 6% |
Unknown | 17 | 22% |