Title |
Brain white matter integrity and association with age at onset in pediatric obsessive-compulsive disorder
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Published in |
Biology of Mood & Anxiety Disorders, December 2014
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DOI | 10.1186/s13587-014-0013-6 |
Pubmed ID | |
Authors |
Isabelle M Rosso, Elizabeth A Olson, Jennifer C Britton, S Evelyn Stewart, George Papadimitriou, William DS Killgore, Nikos Makris, Sabine Wilhelm, Michael A Jenike, Scott L Rauch |
Abstract |
Obsessive-compulsive disorder (OCD) is a common and debilitating neuropsychiatric illness thought to involve abnormal connectivity of widespread brain networks, including frontal-striatal-thalamic circuits. At least half of OCD cases arise in childhood and their underlying neuropathology may differ at least in part from that of adult-onset OCD. Yet, only a few studies have examined brain white matter (WM) integrity in childhood-onset OCD using diffusion tensor imaging (DTI), and none have examined potential associations with age at onset. |
X Demographics
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Italy | 1 | 2% |
Unknown | 51 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 17% |
Student > Ph. D. Student | 6 | 12% |
Student > Master | 6 | 12% |
Student > Doctoral Student | 3 | 6% |
Student > Bachelor | 3 | 6% |
Other | 9 | 17% |
Unknown | 16 | 31% |
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Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 5 | 10% |
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