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Longitudinal evaluation of humoral immune response and merozoite surface antigen diversity in calves naturally infected with Babesia bovis, in São Paulo, Brazil

Overview of attention for article published in Revista Brasileira de Parasitologia Veterinária, December 2017
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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Title
Longitudinal evaluation of humoral immune response and merozoite surface antigen diversity in calves naturally infected with Babesia bovis, in São Paulo, Brazil
Published in
Revista Brasileira de Parasitologia Veterinária, December 2017
DOI 10.1590/s1984-29612017069
Pubmed ID
Authors

Carlos António Matos, Luiz Ricardo Gonçalves, Dasiel Obregón Alvarez, Carla Roberta Freschi, Jenevaldo Barbosa da Silva, Silvana Pompeia Val-Moraes, Natalia Serra Mendes, Marcos Rogério André, Rosangela Zacarias Machado

Abstract

Babesiosis is an economically important infectious disease affecting cattle worldwide. In order to longitudinally evaluate the humoral immune response against Babesia bovis and the merozoite surface antigen diversity of B. bovis among naturally infected calves in Taiaçu, Brazil, serum and DNA samples from 15 calves were obtained quarterly, from their birth to 12 months of age. Anti-B. bovis IgG antibodies were detected by means of the indirect fluorescent antibody test (IFAT) and enzyme-linked immunosorbent assay (ELISA). The polymerase chain reaction (PCR) was used to investigate the genetic diversity of B. bovis, based on the genes that encode merozoite surface antigens (MSA-1, MSA-2b and MSA-2c). The serological results demonstrated that up to six months of age, all the calves developed active immunity against B. bovis. Among the 75 DNA samples evaluated, 2, 4 and 5 sequences of the genes msa-1, msa-2b and msa-2c were obtained. The present study demonstrated that the msa-1 and msa-2b genes sequences amplified from blood DNA of calves positive to B. bovis from Taiaçu were genetically distinct, and that msa-2c was conserved. All animals were serologically positive to ELISA and IFAT, which used full repertoire of parasite antigens in despite of the genetic diversity of MSAs.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 25%
Student > Doctoral Student 3 15%
Student > Bachelor 2 10%
Student > Master 1 5%
Other 1 5%
Other 0 0%
Unknown 8 40%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 5 25%
Agricultural and Biological Sciences 3 15%
Biochemistry, Genetics and Molecular Biology 1 5%
Immunology and Microbiology 1 5%
Medicine and Dentistry 1 5%
Other 1 5%
Unknown 8 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2018.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Revista Brasileira de Parasitologia Veterinária
#333
of 660 outputs
Outputs of similar age
#338,762
of 444,941 outputs
Outputs of similar age from Revista Brasileira de Parasitologia Veterinária
#5
of 14 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 660 research outputs from this source. They receive a mean Attention Score of 1.2. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 444,941 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.