@Food4ears @LieveToet @MarkWendrich @jhn_steen @vrijheidclaimen @enjoyerik2 @MarKes1900 Nog even 10 seconden gezocht: https://t.co/G03LWNZJHI
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RT @DeltaVaran: This is AM404, a metabolite of Tylenol (Acetaminophen/Paracetamol), it binds to the TRPV1 nociceptor It's also a CB1 recep…
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This is AM404, a metabolite of Tylenol (Acetaminophen/Paracetamol), it binds to the TRPV1 nociceptor It's also a CB1 receptor ligand, yup, endocannabinoid All this plays a role in the analgesia provided by this drug :D https://t.co/Ft1tru60Ca https://t.
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AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity https://t.co/TzxCOd21HY