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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A Simple Platform for the Rapid Development of Antimicrobials
|
|---|---|
| Published in |
Scientific Reports, December 2017
|
| DOI | 10.1038/s41598-017-17941-7 |
| Pubmed ID | |
| Authors |
Stephen Albert Johnston, Valeriy Domenyuk, Nidhi Gupta, Milene Tavares Batista, John C. Lainson, Zhan-Gong Zhao, Joel F. Lusk, Andrey Loskutov, Zbigniew Cichacz, Phillip Stafford, Joseph Barten Legutki, Chris W. Diehnelt |
| Abstract |
Recent infectious outbreaks highlight the need for platform technologies that can be quickly deployed to develop therapeutics needed to contain the outbreak. We present a simple concept for rapid development of new antimicrobials. The goal was to produce in as little as one week thousands of doses of an intervention for a new pathogen. We tested the feasibility of a system based on antimicrobial synbodies. The system involves creating an array of 100 peptides that have been selected for broad capability to bind and/or kill viruses and bacteria. The peptides are pre-screened for low cell toxicity prior to large scale synthesis. Any pathogen is then assayed on the chip to find peptides that bind or kill it. Peptides are combined in pairs as synbodies and further screened for activity and toxicity. The lead synbody can be quickly produced in large scale, with completion of the entire process in one week. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mauritius | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 31 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 19% |
| Student > Master | 5 | 16% |
| Student > Doctoral Student | 4 | 13% |
| Student > Ph. D. Student | 4 | 13% |
| Student > Bachelor | 1 | 3% |
| Other | 4 | 13% |
| Unknown | 7 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 19% |
| Agricultural and Biological Sciences | 4 | 13% |
| Chemistry | 3 | 10% |
| Medicine and Dentistry | 3 | 10% |
| Chemical Engineering | 2 | 6% |
| Other | 6 | 19% |
| Unknown | 7 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2023.
All research outputs
#1,344,740
of 24,453,338 outputs
Outputs from Scientific Reports
#13,000
of 133,190 outputs
Outputs of similar age
#31,134
of 448,457 outputs
Outputs of similar age from Scientific Reports
#432
of 4,200 outputs
Altmetric has tracked 24,453,338 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 133,190 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.6. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 448,457 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 4,200 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.