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Biflorin: an o-naphthoquinone of clinical significance

Overview of attention for article published in Anais da Academia Brasileira de Ciências, December 2014
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Title
Biflorin: an o-naphthoquinone of clinical significance
Published in
Anais da Academia Brasileira de Ciências, December 2014
DOI 10.1590/0001-3765201420140085
Pubmed ID
Authors

GABRIELLE G.N.S. WISINTAINER, EVELYNE R.B. SIMÕES, TELMA L.G. LEMOS, SIDNEI MOURA, LUCIANA G.S. SOUZA, ALUISIO M. FONSECA, MANOEL ODORICO MORAES, CLAUDIA PESSOA, MARIANA ROESCH-ELY, JOÃO A.P. HENRIQUES

Abstract

Biflorin is an o-naphthoquinone with proven cytotoxic effects on tumor cells showing antimicrobial, antitumor and antimutagenic activities. Biflorin is an isolated compound taken from the roots of the plant Capraria biflora L. (Schrophulariaceae), indigenous of the West Indies and South America, which is located in temperate or tropical areas. This compound has shown to be strongly active against grampositive and alcohol-acid-resistant bacteria. It has been efficient in inhibiting the proliferation tumor cell lines CEM, HL-60, B16, HCT-8 and MCF-7. Recently, SK-Br3 cell line was treated with biflorin showing important cytotoxic effects. In this article, information related to the first structural characterization studies are presented, as well as the latest reports concerning the biological activity of this molecule.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 24%
Professor 4 14%
Student > Doctoral Student 2 7%
Researcher 2 7%
Librarian 1 3%
Other 3 10%
Unknown 10 34%
Readers by discipline Count As %
Chemistry 3 10%
Pharmacology, Toxicology and Pharmaceutical Science 3 10%
Chemical Engineering 2 7%
Agricultural and Biological Sciences 2 7%
Environmental Science 1 3%
Other 4 14%
Unknown 14 48%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2015.
All research outputs
#11,064,267
of 12,446,028 outputs
Outputs from Anais da Academia Brasileira de Ciências
#195
of 318 outputs
Outputs of similar age
#216,691
of 266,149 outputs
Outputs of similar age from Anais da Academia Brasileira de Ciências
#9
of 11 outputs
Altmetric has tracked 12,446,028 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 318 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,149 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.