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Characterisation and manipulation of docetaxel resistant prostate cancer cell lines

Overview of attention for article published in Molecular Cancer, October 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
patent
1 patent

Citations

dimensions_citation
168 Dimensions

Readers on

mendeley
129 Mendeley
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Title
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines
Published in
Molecular Cancer, October 2011
DOI 10.1186/1476-4598-10-126
Pubmed ID
Authors

Amanda J O'Neill, Maria Prencipe, Catherine Dowling, Yue Fan, Laoighse Mulrane, William M Gallagher, Darran O'Connor, Robert O'Connor, Aoife Devery, Claire Corcoran, Sweta Rani, Lorraine O'Driscoll, John M Fitzpatrick, R William G Watson

Abstract

There is no effective treatment strategy for advanced castration-resistant prostate cancer. Although Docetaxel (Taxotere®) represents the most active chemotherapeutic agent it only gives a modest survival advantage with most patients eventually progressing because of inherent or acquired drug resistance. The aims of this study were to further investigate the mechanisms of resistance to Docetaxel. Three Docetaxel resistant sub-lines were generated and confirmed to be resistant to the apoptotic and anti-proliferative effects of increasing concentrations of Docetaxel.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
India 1 <1%
Russia 1 <1%
Unknown 126 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 24%
Researcher 21 16%
Student > Master 14 11%
Student > Bachelor 14 11%
Other 9 7%
Other 20 16%
Unknown 20 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 28 22%
Agricultural and Biological Sciences 28 22%
Medicine and Dentistry 25 19%
Pharmacology, Toxicology and Pharmaceutical Science 7 5%
Engineering 5 4%
Other 13 10%
Unknown 23 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2023.
All research outputs
#3,138,593
of 25,374,647 outputs
Outputs from Molecular Cancer
#218
of 1,919 outputs
Outputs of similar age
#16,532
of 148,146 outputs
Outputs of similar age from Molecular Cancer
#2
of 17 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,919 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 148,146 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.