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Assessment of nutritional status and health-related quality of life before and after liver transplantation

Overview of attention for article published in BMC Gastroenterology, January 2015
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Title
Assessment of nutritional status and health-related quality of life before and after liver transplantation
Published in
BMC Gastroenterology, January 2015
DOI 10.1186/s12876-015-0232-3
Pubmed ID
Authors

María Teresa García-Rodríguez, María del Carmen Piñón-Villar, Beatriz López-Calviño, Alejandra Otero-Ferreiro, Francisco Suárez-López, Manuel Gómez-Gutiérrez, Salvador Pita-Fernández

Abstract

BackgroundPatients with chronic liver disease frequently suffer from malnutrition, together with a decline in their health-related quality of life.This study was carried out with the aim of evaluating the nutritional status, complications of medical and surgical care, anxiety, health-related quality of life and dependence level on basic and instrumental activities of daily living in pre- and post-liver transplant patients.Methods/DesignA prospective observational study with follow-up of patients on the waiting list for liver transplants who subsequently received a transplant at the University Hospital Complex in A Coruña during the period 2012¿2014 (n¿=¿110).All the patients will be followed-up for a maximum of 6 months. For survivors, assessments will be re-evaluated at one, three and six months post- transplant.Informed consent of the patient and ethical review board approval was obtained (Code: 2010/081 and 2010/082)The following variables will be studied: socio-demographic data, reason for the transplant, comorbidity (Charlson Score), analytical parameters, time on transplant waiting list and post-transplant complications. A trained nurse will evaluate the following for each patient: nutritional indices, anthropometric variables and handgrip strength. Validated questionnaires will be used to determine the patients¿ nutritional status (Subjective Global Assessment), anxiety (STAI questionnaire), Health-Related Quality of Life (LDQoL 1.0 questionnaire), dependence (Barthel Index and Lawton-Brody Scale), nursing diagnoses (NANDA) and post-transplant quality indicators.Multiple linear/logistic regression models will be used to identify variables associated with the events of interest. Changes in nutritional status, quality of life and dependence over time will be analysed with linear mixed-effects regression models.Actuarial survival analysis using Kaplan-Meier curves, Cox regression and competitive risk will be performedConcordance between the different scores that assess nutritional status and interobserver agreement regarding nursing diagnoses will be studied using the statistical Kappa index and Bland Altman method.DiscussionThe risk of malnutrition can be considered as a possible prognostic factor in transplant outcomes, associated with anxiety, health-related quality of life and dependence.For this reason we consider interesting to perform a prospective follow-up study of patients who require a transplant to survive, studying their nutritional status and health-related quality of life.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 1%
Unknown 95 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 19%
Student > Ph. D. Student 10 10%
Student > Bachelor 10 10%
Researcher 9 9%
Student > Postgraduate 8 8%
Other 16 17%
Unknown 25 26%
Readers by discipline Count As %
Medicine and Dentistry 32 33%
Nursing and Health Professions 24 25%
Psychology 3 3%
Biochemistry, Genetics and Molecular Biology 2 2%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 5 5%
Unknown 28 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2015.
All research outputs
#20,249,662
of 22,778,347 outputs
Outputs from BMC Gastroenterology
#1,361
of 1,743 outputs
Outputs of similar age
#295,630
of 351,834 outputs
Outputs of similar age from BMC Gastroenterology
#18
of 23 outputs
Altmetric has tracked 22,778,347 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,743 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,834 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.