Title |
Pathological and molecular diagnosis of bilateral inguinal lymph nodes metastases from low-grade endometrial adenocarcinoma: a case report with review of the literature
|
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Published in |
BMC Cancer, January 2018
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DOI | 10.1186/s12885-017-3944-7 |
Pubmed ID | |
Authors |
Anna Myriam Perrone, Giulia Girolimetti, Simona Cima, Ivana Kurelac, Alessandra Livi, Giacomo Caprara, Donatella Santini, Paolo Castellucci, Alessio Giuseppe Morganti, Giuseppe Gasparre, Pierandrea De Iaco |
Abstract |
Extra-abdominal metastases in low grade endometrial carcinoma are rare events. Inguinal lymphatic spread occurs usually in advanced disease and is associated with abdominal lymph nodes involvement. To our knowledge, isolated inguinal lymph node metastases in patients with early endometrial carcinoma have never been described thus far. We present an uncommon case of inguinal lymph node metastasis in a 51-year old patient with early endometrial disease without other metastatic involvement. The metastatic loci were analyzed with the recently validated method of mitochondrial DNA sequencing to demonstrate clonality of the lesions. We describe the first case of inguinal metastasis from intramucous endometrial carcinoma; this case confirms the unpredictable spread of endometrial neoplasia and the importance of both patient's history and physical examination in good clinical practice. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 13 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 4 | 31% |
Student > Doctoral Student | 2 | 15% |
Student > Bachelor | 2 | 15% |
Researcher | 1 | 8% |
Professor > Associate Professor | 1 | 8% |
Other | 0 | 0% |
Unknown | 3 | 23% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 5 | 38% |
Biochemistry, Genetics and Molecular Biology | 2 | 15% |
Immunology and Microbiology | 1 | 8% |
Computer Science | 1 | 8% |
Unknown | 4 | 31% |