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Neurodegenerative Diseases

Overview of attention for book
Cover of 'Neurodegenerative Diseases'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Acuted Disseminated Encephalomyelitis
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    Chapter 2 Age-Related Macular Degeneration
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    Chapter 3 Arachnoid Cysts
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    Chapter 4 Autism Spectrum Disorders: Information for Pediatricians Supporting Families of Young Children on the Spectrum
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    Chapter 5 Autosomal Recessive Charcot-Marie-Tooth Neuropathy
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    Chapter 6 Creutzfeldt-Jakob disease.
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    Chapter 7 Epigenetics in autism and other neurodevelopmental diseases.
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    Chapter 8 Epilepsy and Epileptic Syndrome
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    Chapter 9 Frontotemporal Lobar Degeneration.
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    Chapter 10 Neurodegenerative Diseases
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    Chapter 11 Juvenile Neuronal Ceroid Lipofuscinoses
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    Chapter 12 Neurodegenerative Diseases
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    Chapter 13 Leukodystrophies
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    Chapter 14 Machado-Joseph Disease and other Rare Spinocerebellar Ataxias.
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    Chapter 15 Neurodegenerations induced by organophosphorous compounds.
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    Chapter 16 Mitochondrial Importance in Alzheimer’s, Huntington’s and Parkinson’s Diseases
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    Chapter 17 Multiple sclerosis.
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    Chapter 18 Myotonic Dystrophy Type 1 or Steinert’s Disease
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    Chapter 19 Neurodegeneration in diabetes mellitus.
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    Chapter 20 Neurofibromatoses
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    Chapter 21 Oxidative stress in developmental brain disorders.
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    Chapter 22 Oxidative Stress and Mitochondrial Dysfunction in Down Syndrome
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    Chapter 23 Pick’s Disease
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    Chapter 24 Premature Aging Syndrome
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    Chapter 25 The savant syndrome and its possible relationship to epilepsy.
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    Chapter 26 Sjogren-Larsson Syndrome
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    Chapter 27 The spinocerebellar ataxias: clinical aspects and molecular genetics.
  29. Altmetric Badge
    Chapter 28 Tourette syndrome.
Attention for Chapter 17: Multiple sclerosis.
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Chapter title
Multiple sclerosis.
Chapter number 17
Book title
Neurodegenerative Diseases
Published in
Advances in experimental medicine and biology, March 2012
DOI 10.1007/978-1-4614-0653-2_17
Pubmed ID
Book ISBNs
978-1-4614-0652-5, 978-1-4614-0653-2
Authors

Miller E, Elżbieta Miller

Abstract

Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and disruption of blood-brain barrier are involved.(1,2) Exacerbations of MS symptoms reflect inflammatory episodes, while the neurodegenerative aspects of gliosis and axonal loss result in the progression of disability. The precise aetiology of MS is not yet known, although epidemiological data indicate that it arises from a complex interactions between genetic susceptibility and environmental factors.(3) In this chapter the brain structures and processes involved in immunopathogenesis of MS are presented. Additionally, clinical phenotypes and biomarkers of MS are showed.

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Italy 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 25%
Student > Ph. D. Student 7 18%
Student > Bachelor 7 18%
Student > Master 6 15%
Student > Doctoral Student 3 8%
Other 5 13%
Unknown 2 5%
Readers by discipline Count As %
Medicine and Dentistry 15 38%
Agricultural and Biological Sciences 9 23%
Neuroscience 3 8%
Biochemistry, Genetics and Molecular Biology 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 1 3%
Unknown 8 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2012.
All research outputs
#2,900,947
of 3,635,033 outputs
Outputs from Advances in experimental medicine and biology
#696
of 971 outputs
Outputs of similar age
#219,094
of 275,594 outputs
Outputs of similar age from Advances in experimental medicine and biology
#45
of 79 outputs
Altmetric has tracked 3,635,033 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 971 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
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We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.