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Dalbavancin treatment in a deep sternal wound MRSA infection after coronary artery bypass surgery: a case report

Overview of attention for article published in Journal of Cardiothoracic Surgery, January 2018
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Mentioned by

twitter
3 tweeters

Citations

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5 Dimensions

Readers on

mendeley
7 Mendeley
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Title
Dalbavancin treatment in a deep sternal wound MRSA infection after coronary artery bypass surgery: a case report
Published in
Journal of Cardiothoracic Surgery, January 2018
DOI 10.1186/s13019-017-0690-5
Pubmed ID
Authors

Aneta GUZEK, Grzegorz SUWALSKI, Dariusz TOMASZEWSKI, Zbigniew RYBICKI

Abstract

A deep sternal wound infection (DSWI) can become a severe complication after cardiac surgery, with in-hospital mortality rates reaching up to 35%. Staphylococci, particularly methicillin resistant Staphylococcus aureus (MRSA), play important roles in its etiology. This case report presents a patient who underwent coronary artery bypass surgery, and suffered postoperatively from a DSWI caused by MRSA. The pathogen was susceptible to vancomycin and rifampicin in vitro; however, this therapy was clinically ineffective. Both clinical improvement and MRSA eradication were achieved after surgical debridement of the wound and the intravenous administration of dalbavancin. We decided to administer dalbavancin because of its convenient pharmacological profile. The patient's tolerance of the antimicrobial was good, the biochemical markers of inflammation returned to the normal ranges, and the microbiological results one week after the dalbavancin administration were negative. A good clinical outcome was achieved with both the surgery and antimicrobial administration. In this case, dalbavancin was more effective in the treatment of the sternal and surrounding tissue infections caused by MRSA, when compared to vancomycin.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 2 29%
Student > Ph. D. Student 1 14%
Student > Postgraduate 1 14%
Student > Master 1 14%
Unknown 2 29%
Readers by discipline Count As %
Medicine and Dentistry 2 29%
Immunology and Microbiology 1 14%
Materials Science 1 14%
Nursing and Health Professions 1 14%
Unknown 2 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2018.
All research outputs
#8,848,768
of 14,123,042 outputs
Outputs from Journal of Cardiothoracic Surgery
#176
of 598 outputs
Outputs of similar age
#225,387
of 397,154 outputs
Outputs of similar age from Journal of Cardiothoracic Surgery
#11
of 27 outputs
Altmetric has tracked 14,123,042 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 598 research outputs from this source. They receive a mean Attention Score of 2.4. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,154 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.