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Evaluation of a Cryptococcal antigen Lateral Flow Assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia

Overview of attention for article published in Revista do Instituto de Medicina Tropical de São Paulo, December 2017
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Title
Evaluation of a Cryptococcal antigen Lateral Flow Assay in serum and cerebrospinal fluid for rapid diagnosis of cryptococcosis in Colombia
Published in
Revista do Instituto de Medicina Tropical de São Paulo, December 2017
DOI 10.1590/s1678-9946201759076
Pubmed ID
Authors

Diego H. Cáceres, Alejandra Zuluaga, Ángela M. Tabares, Tom Chiller, Ángel González, Beatriz L. Gómez

Abstract

A Lateral Flow Assay to detect cryptococcal antigen (CrAg® LFA) in serum and cerebrospinal fluid for the rapid diagnosis of cryptococcosis was evaluated. A retrospective validation was performed. Sensitivity and specificity of the CrAg® LFA was 100%. High concordance (kappa index=1.0) between Cryptococcal Antigen Latex Agglutination System (CALAS®) and CrAg® LFA was observed. CrAg® LFA showed higher analytical sensitivity for detecting low concentrations of cryptococcal antigen.

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 16%
Other 3 12%
Student > Postgraduate 3 12%
Student > Master 3 12%
Student > Ph. D. Student 2 8%
Other 4 16%
Unknown 6 24%
Readers by discipline Count As %
Medicine and Dentistry 10 40%
Immunology and Microbiology 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Social Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 2 8%
Unknown 8 32%