Title |
Isopentylated diphenyl ether derivatives from the fermentation products of an endophytic fungus Phomopsis fukushii
|
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Published in |
The Journal of Antibiotics, January 2018
|
DOI | 10.1038/s41429-017-0006-y |
Pubmed ID | |
Authors |
Zhen-Jie Li, Hai-Ying Yang, Jing Li, Xin Liu, Lin Ye, Wei-Song Kong, Shi-Yun Tang, Gang Du, Zhi-Hua Liu, Min Zhou, Guang-Yu Yang, Qiu-Fen Hu, Xue-Mei Li |
Abstract |
Three new isopentylated diphenyl ethers, (1-3), together with two known isopentylated diphenyl ethers derivatives (4 and 5) were isolated from the fermentation products of an endophytic fungus Phomopsis fukushii. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-3 were evaluated for their anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activity. The results showed that compounds 1-3 showed strong activity with diameter of inhibition zone (IZD) of 21.8 ± 2.4 mm, 16.8 ± 2.2 mm, and 15.6 ± 2.0 mm, respectively. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 1 | 10% |
Lecturer | 1 | 10% |
Student > Doctoral Student | 1 | 10% |
Student > Ph. D. Student | 1 | 10% |
Professor > Associate Professor | 1 | 10% |
Other | 0 | 0% |
Unknown | 5 | 50% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 2 | 20% |
Agricultural and Biological Sciences | 1 | 10% |
Chemistry | 1 | 10% |
Unknown | 6 | 60% |