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Tumour-stroma interactions: Phenotypic and genetic alterations in mammary stroma: implications for tumour progression

Overview of attention for article published in Breast Cancer Research, December 2001
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3 Wikipedia pages

Citations

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85 Dimensions

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28 Mendeley
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Title
Tumour-stroma interactions: Phenotypic and genetic alterations in mammary stroma: implications for tumour progression
Published in
Breast Cancer Research, December 2001
DOI 10.1186/bcr325
Pubmed ID
Authors

Seth L Schor, Ana M Schor

Abstract

In addition to the well documented role of cytokines in mediating tissue-level interactions, it is now clear that matrix macromolecules fulfil a complementary regulatory function. Data highlighted in the present review extend the repertoire of matrix signalling mechanisms, (1) introducing the concept of 'matrikines', these defined as proteinase-generated fragments of matrix macromolecules that display cryptic bioactivities not manifested by the native, full-length form of the molecule, and (2) indicating that a previously identified motogenic factor (migration stimulating factor [MSF]) produced by foetal and cancer patient fibroblasts is a genetically generated truncated isoform of fibronectin, which displays bioactivities cryptic in all previously identified fibronectin isoforms. These observations are discussed in the context of the contribution of a 'foetal-like' stroma to the progression of breast cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
United States 1 4%
Canada 1 4%
Unknown 25 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 18%
Researcher 5 18%
Professor > Associate Professor 4 14%
Student > Bachelor 3 11%
Student > Doctoral Student 3 11%
Other 7 25%
Unknown 1 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 50%
Biochemistry, Genetics and Molecular Biology 7 25%
Medicine and Dentistry 4 14%
Chemistry 1 4%
Engineering 1 4%
Other 0 0%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2017.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Breast Cancer Research
#977
of 2,052 outputs
Outputs of similar age
#32,690
of 132,007 outputs
Outputs of similar age from Breast Cancer Research
#3
of 5 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 132,007 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.