Title |
Positive Effects of Methylphenidate on Social Communication and Self-Regulation in Children with Pervasive Developmental Disorders and Hyperactivity
|
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Published in |
Journal of Autism and Developmental Disorders, August 2008
|
DOI | 10.1007/s10803-008-0636-9 |
Pubmed ID | |
Authors |
Laudan B. Jahromi, Connie L. Kasari, James T. McCracken, Lisa S-Y. Lee, Michael G. Aman, Christopher J. McDougle, Lawrence Scahill, Elaine Tierney, L. Eugene Arnold, Benedetto Vitiello, Louise Ritz, Andrea Witwer, Erin Kustan, Jaswinder Ghuman, David J. Posey |
Abstract |
This report examined the effect of methylphenidate on social communication and self-regulation in children with pervasive developmental disorders and hyperactivity in a secondary analysis of RUPP Autism Network data. Participants were 33 children (29 boys) between the ages of 5 and 13 years who participated in a four-week crossover trial of placebo and increasing doses of methylphenidate given in random order each for one week. Observational measures of certain aspects of children's social communication, self-regulation, and affective behavior were obtained each week. A significant positive effect of methylphenidate was seen on children's use of joint attention initiations, response to bids for joint attention, self-regulation, and regulated affective state. The results go beyond the recent literature and suggest that methylphenidate may have positive effects on social behaviors in children with PDD and hyperactivity. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 1% |
Brazil | 2 | 1% |
Germany | 1 | <1% |
Ireland | 1 | <1% |
Japan | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 186 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 28 | 14% |
Student > Ph. D. Student | 27 | 14% |
Student > Master | 21 | 11% |
Student > Doctoral Student | 20 | 10% |
Professor > Associate Professor | 14 | 7% |
Other | 48 | 25% |
Unknown | 36 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 66 | 34% |
Medicine and Dentistry | 30 | 15% |
Social Sciences | 15 | 8% |
Agricultural and Biological Sciences | 7 | 4% |
Neuroscience | 7 | 4% |
Other | 22 | 11% |
Unknown | 47 | 24% |