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Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM

Overview of attention for article published in Anais da Academia Brasileira de Ciências, October 2017
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Title
Surface, thermal and hemocompatible properties of novel single stage electrospun nanocomposites comprising polyurethane blended with bio oilTM
Published in
Anais da Academia Brasileira de Ciências, October 2017
DOI 10.1590/0001-3765201720170230
Pubmed ID
Authors

MANIKANDAN AYYAR, MOHAN PRASATH MANI, SARAVANA KUMAR JAGANATHAN, RAJASEKAR RATHINASAMY, AHMAD ZAHRAN KHUDZARI, NAVANEETHA PANDIYARAJ KRISHNASAMY

Abstract

In this work, the physicochemical and blood compatibility properties of prepared PU/Bio oil nanocomposites were investigated. Scanning electron microscope (SEM) studies revealed the reduction of mean fiber diameter (709 ± 211 nm) compared to the pristine PU (969 nm ± 217 nm). Fourier transform infrared spectroscopy (FTIR) analysis exposed the characteristic peaks of pristine PU. Composite peak intensities were decreased insinuating the interaction of the bio oilTM with the PU. Contact angle analysis portrayed the hydrophobic nature of the fabricated patch compared to pristine PU. Thermal gravimetric analysis (TGA) depicted the better thermal stability of the novel nanocomposite patch and its different thermal behavior in contrast with the pristine PU. Atomic force microscopy (AFM) analysis revealed the increase in the surface roughness of the composite patch. Activated partial thromboplastin time (APTT) and prothrombin time (PT) signified the novel nanocomposite patch ability in reducing the thrombogenicity and promoting the anticoagulant nature. Finally the hemolytic percentage of the fabricated composite was in the acceptable range revealing its safety and compatibility with the red blood cells. To reinstate, the fabricated patch renders promising physicochemical and blood compatible nature making it a new putative candidate for wound healing application.

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 25%
Professor > Associate Professor 2 13%
Other 1 6%
Student > Postgraduate 1 6%
Student > Ph. D. Student 1 6%
Other 3 19%
Unknown 4 25%
Readers by discipline Count As %
Engineering 5 31%
Chemistry 2 13%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Agricultural and Biological Sciences 1 6%
Medicine and Dentistry 1 6%
Other 3 19%
Unknown 3 19%