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Phasing in on the cell cycle

Overview of attention for article published in Cell Division, January 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#5 of 105)
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

twitter
16 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
20 Dimensions

Readers on

mendeley
85 Mendeley
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Title
Phasing in on the cell cycle
Published in
Cell Division, January 2018
DOI 10.1186/s13008-018-0034-4
Pubmed ID
Authors

Steven Boeynaems, Peter Tompa, Ludo Van Den Bosch

Abstract

Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase transition has claimed the spotlight in recent years as a novel way of how cells compartmentalize and regulate biochemical reactions. Moreover, this discovery has provided a new framework for the study of membrane-less organelle biogenesis and protein aggregation in neurodegenerative disorders. We now argue that this framework could be useful in the study of cell cycle regulation and cancer. Based on our work on phase transitions of arginine-rich proteins in neurodegeneration, via combining mass spectroscopy with bioinformatics analyses, we found that also numerous proteins involved in the regulation of the cell cycle can undergo protein phase separation. Indeed, several proteins whose function affects the cell cycle or are associated with cancer, have been recently found to phase separate from the test tube to cells. Investigating the role of this process for cell cycle proteins and understanding its molecular underpinnings will provide pivotal insights into the biology of cell cycle progression and cancer.

Twitter Demographics

The data shown below were collected from the profiles of 16 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 26%
Researcher 15 18%
Student > Master 10 12%
Student > Bachelor 6 7%
Student > Postgraduate 5 6%
Other 16 19%
Unknown 11 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 31 36%
Agricultural and Biological Sciences 10 12%
Chemistry 7 8%
Neuroscience 5 6%
Chemical Engineering 4 5%
Other 15 18%
Unknown 13 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 April 2018.
All research outputs
#1,934,707
of 16,562,219 outputs
Outputs from Cell Division
#5
of 105 outputs
Outputs of similar age
#59,304
of 372,140 outputs
Outputs of similar age from Cell Division
#1
of 1 outputs
Altmetric has tracked 16,562,219 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 105 research outputs from this source. They receive a mean Attention Score of 2.8. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 372,140 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them