Chapter title |
Ribotypes and New Virulent Strains Across Europe
|
---|---|
Chapter number | 4 |
Book title |
Updates on Clostridium difficile in Europe
|
Published in |
Advances in experimental medicine and biology, January 2018
|
DOI | 10.1007/978-3-319-72799-8_4 |
Pubmed ID | |
Book ISBNs |
978-3-31-972798-1, 978-3-31-972799-8
|
Authors |
Jeanne Couturier, Kerrie Davies, Cécile Gateau, Frédéric Barbut, Couturier, Jeanne, Davies, Kerrie, Gateau, Cécile, Barbut, Frédéric |
Abstract |
Clostridium difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology of C. difficile infections (CDI) has dramatically changed since the early 2000s, with an increasing incidence and severity across Europe. This trend is partly due to the emergence and rapid worldwide spread of the hypervirulent and epidemic PCR ribotype 027. Profiles of patients with CDI have also evolved, with description of community-acquired (CA) infections in patients with no traditional risk factors for CDI. However, recent epidemiological studies indicated that some European countries have successfully controlled the dissemination of the 027 clone whereas other countries recently reported the emergence of other virulent or unusual strains. The aims of this review are to summarize the current European CDI epidemiology and to describe the new virulent C. difficile strains circulating in Europe, as well as other potential emerging strains described elsewhere. Standardized typing methods and surveillance programmes are mandatory for a better understanding and monitoring of CDI in Europe. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 21% |
Student > Doctoral Student | 4 | 17% |
Professor | 3 | 13% |
Other | 2 | 8% |
Student > Master | 2 | 8% |
Other | 3 | 13% |
Unknown | 5 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 4 | 17% |
Biochemistry, Genetics and Molecular Biology | 3 | 13% |
Medicine and Dentistry | 3 | 13% |
Immunology and Microbiology | 3 | 13% |
Nursing and Health Professions | 1 | 4% |
Other | 0 | 0% |
Unknown | 10 | 42% |