Chapter title |
Faecal Microbiota Transplantation as Emerging Treatment in European Countries
|
---|---|
Chapter number | 11 |
Book title |
Updates on Clostridium difficile in Europe
|
Published in |
Advances in experimental medicine and biology, January 2018
|
DOI | 10.1007/978-3-319-72799-8_11 |
Pubmed ID | |
Book ISBNs |
978-3-31-972798-1, 978-3-31-972799-8
|
Authors |
Marcello Maida, James Mcilroy, Gianluca Ianiro, Giovanni Cammarota, Maida, Marcello, Mcilroy, James, Ianiro, Gianluca, Cammarota, Giovanni |
Abstract |
Clostridium difficile infection (CDI) is one of the most common healthcare-associated infections in the world and is a leading cause of morbidity and mortality in hospitalized patients.Although several antibiotics effectively treat CDI, some individuals do not respond to these drugs and may be cured by transplanting stool from healthy donors. This procedure, termed Faecal Microbiota Transplantation (FMT), has demonstrated remarkable efficacy as a treatment for recurrent CDI.FMT has also been investigated in other diseases and disorders where perturbations to the gut microbiota have been theorized to play a causative role in pathogenesis and severity, such as inflammatory bowel disease (IBD). Although FMT is currently not recommended to cure IBD patients in clinical practice, several studies have recently been carried out with promising results. The aim of future research is therefore to standardize protocols and develop FMT as a therapeutic option for these patients.This review summarizes data on the use of FMT as a treatment for CDI and IBD, with special attention given to studies conducted in European countries. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 16% |
Student > Doctoral Student | 4 | 13% |
Student > Bachelor | 3 | 10% |
Student > Postgraduate | 2 | 6% |
Lecturer | 1 | 3% |
Other | 5 | 16% |
Unknown | 11 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 26% |
Immunology and Microbiology | 4 | 13% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Nursing and Health Professions | 1 | 3% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Other | 3 | 10% |
Unknown | 12 | 39% |